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Carmil1 Gene Detail
Summary
  • Symbol
    Carmil1
  • Name
    capping protein regulator and myosin 1 linker 1
  • Synonyms
    1110037D04Rik, Carmil, Lrrc16, Lrrc16a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915982
    NCBI Gene: 68732
  • Gene Overview
    MyGene.info: CARMIL1
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:24012481-24280790 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 10.05 cM, cytoband A3.2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2494 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915982
 protein coding gene Chr13:24012344-24280795 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020376
 protein coding gene Chr13:21466107-21744389 (-)
A/J MGP_AJ_G0020325
 protein coding gene Chr13:21069699-21338930 (-)
AKR/J MGP_AKRJ_G0020305
 protein coding gene Chr13:21327777-21597293 (-)
BALB/cJ MGP_BALBcJ_G0020323
 protein coding gene Chr13:21063753-21331218 (-)
C3H/HeJ MGP_C3HHeJ_G0020127
 protein coding gene Chr13:21400719-21669396 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020760
 protein coding gene Chr13:22247027-22529102 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018348
 protein coding gene Chr13:19843648-20107556 (-)
CAST/EiJ MGP_CASTEiJ_G0019644
 protein coding gene Chr13:21086825-21364329 (-)
CBA/J MGP_CBAJ_G0020081
 protein coding gene Chr13:23103722-23380054 (-)
DBA/2J MGP_DBA2J_G0020207
 protein coding gene Chr13:20598478-20861912 (-)
FVB/NJ MGP_FVBNJ_G0020191
 protein coding gene Chr13:20245720-20507296 (-)
LP/J MGP_LPJ_G0020280
 protein coding gene Chr13:21780600-22052976 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020218
 protein coding gene Chr13:23409411-23685010 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020802
 protein coding gene Chr13:21173259-21442945 (-)
PWK/PhJ MGP_PWKPhJ_G0019398
 protein coding gene Chr13:20637468-20903115 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019213
 protein coding gene Chr13:19992553-20280905 (-)
WSB/EiJ MGP_WSBEiJ_G0019704
 protein coding gene Chr13:21322463-21596229 (-)



Homology
more
  • Human Ortholog
    CARMIL1, capping protein regulator and myosin 1 linker 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CARMIL1, capping protein regulator and myosin 1 linker 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CARMIL, CARMIL1a, dJ501N12.1, dJ501N12.5, LRRC16, LRRC16A
  • Links
    NCBI Gene ID: 55604
    neXtProt AC: NX_Q5VZK9
    UniProt: Q5VZK9

  • Chr Location
    6p22.2; chr6:25279428-25620530 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
No abnormal phenotype was observed in a high-throughput screen, nor in a pathology assessment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    102
  • Tissues
    11
  • cDNA Data
    40
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68732 NCBI Gene Model | MGI Sequence Detail 268310 C57BL/6J ±  kb
transcript NM_001311122 RefSeq | MGI Sequence Detail 5174 C57BL/6  
polypeptide Q6EDY6 UniProt | EBI | MGI Sequence Detail 1374 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145230
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 15
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:218204 Jo YJ, et al., Actin-capping proteins play essential roles in the asymmetric division of maturing mouse oocytes. J Cell Sci. 2015 Jan 1;128(1):160-70
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/11/2019
MGI 6.14 		The Jackson Laboratory