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Ifitm1
Gene Detail
 Symbol
Name
ID
Ifitm1
interferon induced transmembrane protein 1
MGI:1915963
Synonyms 1110036C17Rik, fragilis2, Mil2
Feature Type protein coding gene
Genetic Map
Chromosome 7
86.20 cM, cytoband F5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:140967221-140969825 bp, + strand
From VEGA annotation of GRCm38

  2605 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:135938  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: interferon-induced transmembrane protein
Gene Tree: Ifitm1

Mutations,
alleles, and
phenotypes
All mutations/alleles(65) : Gene trapped(60) Targeted(5)
Genomic Mutations involving Ifitm1 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice exhibited enhanced motor coordination during inverted screen testing when compared with that of their wild-type littermates.
 
Interactions
Ifitm1 interacts with 26 markers (Mir23a, Mir23b, Mir137, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process anterior/posterior pattern specification, defense response to virus, ...
Component integral component of membrane, membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (115)    Tissues (38)    Images (35)
Theiler Stages: 2, 3, 4, 9, 10, 11, 13, 14, 15, 21, 23, 25, 28
Assay TypeResults
RNA in situ 71
RT-PCR 44
cDNA source data(49)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) cDNA(49) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021113 (Evidence)
Ensembl Gene ModelENSMUSG00000025491 (Evidence)
Entrez Gene68713 (Evidence)
UniGene175661
DFCITC1579308, TC1592291
DoTSDT.101206291, DT.537952, DT.91585196
Consensus CDS ProjectCCDS21995.1
International Mouse Knockout Project StatusIfitm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021113 VEGA Gene Model | MGI Sequence Detail 2605 C57BL/6J ±  kb
transcript OTTMUST00000049967 VEGA | MGI Sequence Detail 560 Not Applicable 
polypeptide OTTMUSP00000023251 VEGA | MGI Sequence Detail 106 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(28 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007593 Interferon-induced transmembrane protein
Protein Ontology PR:000002052 interferon-induced transmembrane protein 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199855 Tanaka SS, et al., Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo. PLoS One. 2013;8(3):e57428
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory