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Rabl2
Gene Detail
Symbol

Name
ID
Rabl2
RAB, member RAS oncogene family-like 2
MGI:1915958
Synonyms
1110031N17Rik, Rabl2a
Feature Type
protein coding gene
Genetic Map
Chromosome 15
44.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:89582533-89591923 bp, - strand
From VEGA annotation of GRCm38

  9391 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:90913  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee

Gene Tree: Rabl2

Human
homologs
Human Homolog RABL2A, RAB, member of RAS oncogene family-like 2A
NCBI Gene ID 11159
neXtProt AC  NX_Q9UBK7
Human Chr (Location)  2q13; chr2:113627237-113643398 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Chemically induced (ENU)(1) Gene trapped(1) Radiation induced(1) Targeted(2)
Genomic Mutations involving Rabl2 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced allele exhibit male infertility, reduced testis weight, oligospermia, asthenozoospermia and short flagellum.
 
Interactions
Rabl2 interacts with 107 markers (Mir7-1, Mir30a, Mir30b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cilium assembly, single fertilization, ...
Component intraciliary transport particle B, sperm midpiece
Function GTP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 2
cDNA source data(32)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(32) cDNA(32)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000035204 (Evidence)
Ensembl Gene ModelENSMUSG00000022621 (Evidence)
Entrez Gene68708 (Evidence)
UniGene23258
DFCITC1581622, TC1589225, TC1593435, TC1742922
DoTSDT.101382276, DT.91393383, DT.94241231, DT.97357620, DT.99841668
NIA Mouse Gene IndexU036539
Consensus CDS ProjectCCDS49704.1
International Mouse Knockout Project StatusRabl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035204 VEGA Gene Model | MGI Sequence Detail 9391 C57BL/6J ±  kb
transcript OTTMUST00000089659 VEGA | MGI Sequence Detail 1640 Not Applicable 
polypeptide OTTMUSP00000049018 VEGA | MGI Sequence Detail 223 Not Applicable 

For the selected sequences
All sequences(82) RefSeq(14) UniProt(6)
Polymorphisms
SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR005225 Small GTP-binding protein domain
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969
All references(36)
Other
accession IDs
MGI:2139382

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory