Rabl2
Gene Detail

Symbol Name ID

Rabl2 RAB, member of RAS oncogene family-like 2 MGI:1915958

Synonyms

1110031N17Rik, Rabl2a

Feature Type

protein coding gene

Genetic Map

Chromosome 15

44.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr15:89582533-89591923 bp, - strand From VEGA annotation of GRCm38   9391 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:90913  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rabl2

Human homologs

Human Homolog		RABL2A, RAB, member of RAS oncogene family-like 2A
NCBI Gene ID		11159
neXtProt AC		NX_Q9UBK7
Human Chr (Location)		2q13; chr2:114384817-114400975 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(1) Gene trapped(1) Chemically induced(1)
 

Mice homozygous for an ENU-induced allele exhibit male infertility, reduced testis weight, oligospermia, asthenozoospermia and short flagellum.

 

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	biological_process
Component	cellular_component
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (2)   
Theiler Stages: 11, 13

Assay Type	Results
RNA in situ	2

cDNA source data(32)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(32) cDNA(32)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000035204 (Evidence)
Ensembl Gene Model	ENSMUSG00000022621 (Evidence)
Entrez Gene	68708 (Evidence)
UniGene	23258
DFCI	TC1581622, TC1589225, TC1593435, TC1742922
DoTS	DT.101382276, DT.91393383, DT.94241231, DT.97357620, DT.99841668
NIA Mouse Gene Index	U036539
Consensus CDS Project	CCDS49704.1
International Mouse Knockout Project Status	Rabl2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035204	VEGA Gene Model | MGI Sequence Detail	9391	C57BL/6J
transcript	OTTMUST00000089659	VEGA | MGI Sequence Detail	1640	Not Applicable
polypeptide	OTTMUSP00000049018	VEGA | MGI Sequence Detail	223	Not Applicable

All sequences(74) RefSeq(2) UniProt(10)

Polymorphisms

SNPs(63 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR005225	Small GTP-binding protein domain

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969
All references(34)

Other accession IDs

MGI:2139382