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Ppp1r27 Gene Detail
Summary
  • Symbol
    Ppp1r27
  • Name
    protein phosphatase 1, regulatory subunit 27
  • Synonyms
    1110033I14Rik, Dysfip1, toonin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915951
    NCBI Gene: 68701
  • Gene Overview
    MyGene.info: PPP1R27
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120549979-120551132 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 84.26 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915951
protein coding gene Chr11:120549975-120551132 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019509
protein coding gene Chr11:125019112-125020265 (-)
A/J MGP_AJ_G0019477
protein coding gene Chr11:119459076-119460229 (-)
AKR/J MGP_AKRJ_G0019447
protein coding gene Chr11:123052438-123053591 (-)
BALB/cJ MGP_BALBcJ_G0019452
protein coding gene Chr11:119814397-119815550 (-)
C3H/HeJ MGP_C3HHeJ_G0019258
protein coding gene Chr11:123390199-123391352 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019900
protein coding gene Chr11:128802891-128804044 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017526
protein coding gene Chr11:116450889-116452040 (-)
CAST/EiJ MGP_CASTEiJ_G0018812
protein coding gene Chr11:124883798-124884950 (-)
CBA/J MGP_CBAJ_G0019229
protein coding gene Chr11:133843742-133844895 (-)
DBA/2J MGP_DBA2J_G0019341
protein coding gene Chr11:118828383-118829536 (-)
FVB/NJ MGP_FVBNJ_G0019333
protein coding gene Chr11:118539111-118540264 (-)
LP/J MGP_LPJ_G0019413
protein coding gene Chr11:125324446-125325599 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019366
protein coding gene Chr11:132680610-132681763 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019940
protein coding gene Chr11:123741131-123742284 (-)
PWK/PhJ MGP_PWKPhJ_G0018578
protein coding gene Chr11:120262804-120263956 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018370
protein coding gene Chr11:123501568-123502719 (-)
WSB/EiJ MGP_WSBEiJ_G0018864
protein coding gene Chr11:123728389-123729542 (-)



Homology
more
  • Human Ortholog
    PPP1R27, protein phosphatase 1 regulatory subunit 27
  • Vertebrate Orthologs
    11
  • Human Ortholog
    PPP1R27, protein phosphatase 1 regulatory subunit 27
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DYSFIP1
  • Links
    NCBI Gene ID: 116729
    neXtProt AC: NX_Q86WC6
    UniProt: Q86WC6

  • Chr Location
    17q25.3; chr17:81833492-81835050 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025129 Ensembl Gene Model | MGI Sequence Detail 1154 C57BL/6J ±  kb
transcript ENSMUST00000026121 Ensembl | MGI Sequence Detail 771 Not Applicable  
polypeptide ENSMUSP00000026121 Ensembl | MGI Sequence Detail 154 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory