Pga5
Gene Detail

Symbol Name ID

Pga5 pepsinogen 5, group I MGI:1915935

Synonyms

1110035E17Rik, Pepf, pepsinogen A5

Feature Type

protein coding gene

Genetic Map

Chromosome 19

7.12 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:10668957-10678071 bp, - strand From NCBI annotation of GRCm38   9115 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:105932  Vertebrate Homology Class
1 mouse; 1 rat; 31 cattle; 1 dog

Protein SuperFamily: Pepsin
Gene Tree: Pga5

Alleles and phenotypes

All alleles(5) : Targeted(2) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	metabolic process, protein metabolic process, ...
Component	cellular_component
Function	aspartic-type endopeptidase activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (63)    Tissues (37)   
Theiler Stages: 15, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
Immunohistochemistry	2
RNA in situ	11
Northern blot	48
Western blot	2

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(15) cDNA(15)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000024738 (Evidence)
Entrez Gene	58803 (Evidence)
UniGene	34037
DFCI	TC1585006
DoTS	DT.528753
NIA Mouse Gene Index	U038809
Consensus CDS Project	CCDS29584.1
International Mouse Knockout Project Status	Pga5

Sequences

Length	Strain/Species
genomic	58803	NCBI Gene Model | MGI Sequence Detail	9115	C57BL/6J
transcript	NM_021453	RefSeq | MGI Sequence Detail	1416	C57BL/6
polypeptide	NP_067428	RefSeq | MGI Sequence Detail	387	C57BL/6

All sequences(17) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(156 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001461	Peptidase A1
InterPro	IPR021109	Peptidase aspartic
InterPro	IPR001969	Peptidase aspartic, active site
InterPro	IPR009007	Peptidase aspartic, catalytic
InterPro	IPR012848	Propeptide, peptidase A1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:171730 Ogaki S, et al., An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. BMC Dev Biol. 2011;11:13
All references(30)