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Slc44a2 Gene Detail
Summary
  • Symbol
    Slc44a2
  • Name
    solute carrier family 44, member 2
  • Synonyms
    1110028E10Rik, CTL2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915932
    NCBI Gene: 68682
  • Gene Overview
    MyGene.info: SLC44A2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr9:21320719-21355028 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34310 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.77 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC44A2, solute carrier family 44 member 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SLC44A2, solute carrier family 44 member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CTL2, PP1292
  • Links
    NCBI Gene ID: 57153
    neXtProt AC: NX_Q8IWA5
    UniProt: Q8IWA5

  • Chr Location
    19p13.2; chr19:10602445-10644559 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit cochlear hair cell loss, spiral ganglion degeneration, and progressive sensorineural hearing loss.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68682 NCBI Gene Model | MGI Sequence Detail 34310 C57BL/6J ±  kb
    transcript NM_001359227 RefSeq | MGI Sequence Detail 3629 C57BL/6  
    polypeptide Q8BY89 UniProt | EBI | MGI Sequence Detail 706 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      64 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:239440 Kommareddi P, et al., Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2. J Assoc Res Otolaryngol. 2015 Dec;16(6):695-712

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    05/08/2018
    MGI 6.12
    The Jackson Laboratory