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Klk5
Gene Detail
 Symbol
Name
ID
Klk5
kallikrein related-peptidase 5
MGI:1915918
Synonyms 1110030O19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
28.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:43842269-43851181 bp, + strand
From VEGA annotation of GRCm38

  8913 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75000  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Klk5

Human
homologs
Human Homolog KLK5, kallikrein-related peptidase 5
NCBI Gene ID 25818
neXtProt AC  NX_Q9Y337
Human Synonyms  KLKL2, KLK-L2, SCTE
Human Chr (Location)  19q13.33; chr19:50943303-50953088 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix )
Interactions
Klk5 interacts with 39 markers (Mir22, Mir32, Mir148a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process positive regulation of G-protein coupled receptor protein signaling pathway, proteolysis
Component epidermal lamellar body
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027222 (Evidence)
Ensembl Gene ModelENSMUSG00000074155 (Evidence)
Entrez Gene68668 (Evidence)
UniGene458122
DFCITC1587510
DoTSDT.485760
NIA Mouse Gene IndexU068611
Consensus CDS ProjectCCDS21185.1
International Mouse Knockout Project StatusKlk5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027222 VEGA Gene Model | MGI Sequence Detail 8913 C57BL/6J ±  kb
transcript OTTMUST00000067318 VEGA | MGI Sequence Detail 1239 Not Applicable 
polypeptide OTTMUSP00000033847 VEGA | MGI Sequence Detail 293 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(8) UniProt(1)
Polymorphisms SNPs within 2kb(143 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009415 kallikrein-5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory