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Svop Gene Detail
Summary
  • Symbol
    Svop
  • Name
    SV2 related protein
  • Synonyms
    1110030H18Rik, msvop
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915916
    NCBI Gene: 68666
Location & Maps
more
  • Sequence Map
    Chr5:114026910-114091570 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      64661 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 55.94 cM, cytoband F
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SVOP, SV2 related protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SVOP, SV2 related protein
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55530
    neXtProt AC: NX_Q8N4V2

  • Chr Location
    12q24.11; chr12:108908129-109021240 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 41283
    1 human;1 mouse;1 rat;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SVOP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Svop
  • Incidental Mutations
Mice homozygous for a knock-out allele are viable with no phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030561 VEGA Gene Model | MGI Sequence Detail 64661 C57BL/6J ±  kb
transcript OTTMUST00000075684 VEGA | MGI Sequence Detail 3379 Not Applicable  
polypeptide OTTMUSP00000039727 VEGA | MGI Sequence Detail 548 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    631 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 27
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGI:2140865
References
more
  • Summaries
    All 36
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:204383 Yao J, et al., Loss of the SV2-like protein SVOP produces no apparent deficits in laboratory mice. PLoS One. 2013;8(7):e68215

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory