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Fndc1 Gene Detail
Summary
  • Symbol
    Fndc1
  • Name
    fibronectin type III domain containing 1
  • Synonyms
    1110027O12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915905
    NCBI Gene: 68655
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:7738569-7827302 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 4.77 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    680 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915905
protein coding gene Chr17:7738569-7827340 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023120
protein coding gene Chr17:4982908-5072244 (-)
A/J MGP_AJ_G0023094
protein coding gene Chr17:5242556-5331233 (-)
AKR/J MGP_AKRJ_G0023056
protein coding gene Chr17:4404573-4504754 (+)
BALB/cJ MGP_BALBcJ_G0023096
protein coding gene Chr17:5037252-5125280 (-)
C3H/HeJ MGP_C3HHeJ_G0022855
protein coding gene Chr17:5143018-5232741 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023535
protein coding gene Chr17:5249382-5350478 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021038
protein coding gene Chr17:3588595-3677055 (+)
CAST/EiJ MGP_CASTEiJ_G0022366
protein coding gene Chr17:4944697-5032697 (-)
CBA/J MGP_CBAJ_G0022825
protein coding gene Chr17:5598372-5692723 (-)
DBA/2J MGP_DBA2J_G0022964
protein coding gene Chr17:4911963-5000273 (-)
FVB/NJ MGP_FVBNJ_G0022931
protein coding gene Chr17:4826268-4914729 (-)
LP/J MGP_LPJ_G0023025
protein coding gene Chr17:4407874-4505785 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022950
protein coding gene Chr17:5380994-5473355 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023560
protein coding gene Chr17:5113090-5204809 (-)
PWK/PhJ MGP_PWKPhJ_G0022115
protein coding gene Chr17:4479856-4571027 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021942
protein coding gene Chr17:4043139-4131857 (+)
WSB/EiJ MGP_WSBEiJ_G0022422
protein coding gene Chr17:5194248-5284523 (-)



Homology
more
  • Human Ortholog
    FNDC1, fibronectin type III domain containing 1
  • Human Ortholog
    FNDC1, fibronectin type III domain containing 1
    Orthology source: HGNC
  • Synonyms
    AGS8, bA243O10.1, dJ322A24.1, FNDC2, MEL4B3
  • Links
    NCBI Gene ID: 84624
    neXtProt AC: NX_Q4ZHG4
    UniProt: Q4ZHG4

  • Chr Location
    6q25.3; chr6:159169397-159272108 (+)  GRCh38.p7

  • HCOP
    human homology predictions: FNDC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071984 Ensembl Gene Model | MGI Sequence Detail 88734 C57BL/6J ±  kb
transcript ENSMUST00000097425 Ensembl | MGI Sequence Detail 5845 Not Applicable  
polypeptide ENSMUSP00000095036 Ensembl | MGI Sequence Detail 1732 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR003961 Fibronectin type III
    IPR036116 Fibronectin type III superfamily
    IPR013783 Immunoglobulin-like fold
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:36910 You Y, et al., Chromosomal deletion complexes in mice by radiation of embryonic stem cells. Nat Genet. 1997 Mar;15(3):285-8
  • Latest
    J:254511 Inoue K, et al., The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development. Cell Rep. 2017 May 2;19(5):949-956

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory