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Cryl1 Gene Detail
Summary
  • Symbol
    Cryl1
  • Name
    crystallin, lambda 1
  • Synonyms
    1110025H08Rik, A230106J09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915881
    NCBI Gene: 68631
  • Gene Overview
    MyGene.info: CRYL1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:57275034-57398483 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 30.10 cM, cytoband C2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    234 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915881
protein coding gene Chr14:57274993-57398529 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021405
protein coding gene Chr14:51442798-51576249 (-)
A/J MGP_AJ_G0021366
protein coding gene Chr14:50434686-50559159 (-)
AKR/J MGP_AKRJ_G0021341
protein coding gene Chr14:52204249-52327045 (-)
BALB/cJ MGP_BALBcJ_G0021369
protein coding gene Chr14:50379924-50506679 (-)
C3H/HeJ MGP_C3HHeJ_G0021148
protein coding gene Chr14:51853499-51984476 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021808
protein coding gene Chr14:54001821-54135088 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019348
protein coding gene Chr14:48513745-48644775 (-)
CAST/EiJ MGP_CASTEiJ_G0020666
protein coding gene Chr14:48193254-48319988 (-)
CBA/J MGP_CBAJ_G0021115
protein coding gene Chr14:55574946-55718637 (-)
DBA/2J MGP_DBA2J_G0021236
protein coding gene Chr14:50114882-50238301 (-)
FVB/NJ MGP_FVBNJ_G0021217
protein coding gene Chr14:49499551-49623420 (-)
LP/J MGP_LPJ_G0021311
protein coding gene Chr14:52495575-52625630 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021245
protein coding gene Chr14:54959890-55090502 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021832
protein coding gene Chr14:51351386-51479560 (-)
PWK/PhJ MGP_PWKPhJ_G0020409
protein coding gene Chr14:46649271-46774934 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020242
protein coding gene Chr14:47417546-47546982 (-)
WSB/EiJ MGP_WSBEiJ_G0020718
protein coding gene Chr14:51675544-51803823 (-)



Homology
more
  • Human Ortholog
    CRYL1, crystallin lambda 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRYL1, crystallin lambda 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GDH, gul3DH, HEL30, lambda-CRY
  • Links
    NCBI Gene ID: 51084
    neXtProt AC: NX_Q9Y2S2
    UniProt: Q9Y2S2

  • Chr Location
    13q12.11; chr13:20403667-20525873 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68631 NCBI Gene Model | MGI Sequence Detail 123450 C57BL/6J ±  kb
transcript NM_030004 RefSeq | MGI Sequence Detail 1410 C57BL/6  
polypeptide Q99KP3 UniProt | EBI | MGI Sequence Detail 319 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000005920 lambda-crystallin
  • EC
  • InterPro Domains
    IPR022694 3-hydroxyacyl-CoA dehydrogenase
    IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site
    IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
    IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
    IPR013328 6-phosphogluconate dehydrogenase, domain 2
    IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
    IPR036291 NAD(P)-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 64
    cDNA 62
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1925166, MGI:2145872
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory