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Fbxw9 Gene Detail
Summary
  • Symbol
    Fbxw9
  • Name
    F-box and WD-40 domain protein 9
  • Synonyms
    1110017H11Rik, Fbw9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915878
    NCBI Gene: 68628
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:85786748-85793750 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 41.54 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    246 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915878
 protein coding gene Chr8:85786684-85793753 (+)
129S1/SvImJ ENSMUSG00200024464
 protein coding gene Chr8:80151618-80158569 (+)
A/J ENSMUSG00195015007
 protein coding gene Chr8:80509674-80516620 (+)
AKR/J ENSMUSG00220022822
 protein coding gene Chr8:80551245-80558196 (+)
BALB/cJ ENSMUSG00180020047
 protein coding gene Chr8:80350343-80357294 (+)
C3H/HeJ ENSMUSG00175010907
 protein coding gene Chr8:80445353-80452299 (+)
C57BL/6NJ ENSMUSG00215010590
 protein coding gene Chr8:80083012-80090091 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031327
 protein coding gene Chr8:76411371-76418736 (+)
CAST/EiJ ENSTCUG00005036277
 protein coding gene Chr8:79959776-79966595 (+)
CBA/J ENSMUSG00210030683
 protein coding gene Chr8:80432471-80439422 (+)
DBA/2J ENSMUSG00185037300
 protein coding gene Chr8:86541060-86548010 (+)
FVB/NJ ENSMUSG00205035019
 protein coding gene Chr8:79488327-79495277 (+)
JF1/MsJ ENSUMUG00000020540
 protein coding gene Chr8:88849673-88856744 (+)
LP/J ENSMUSG00230024525
 protein coding gene Chr8:90148602-90155553 (+)
NOD/ShiLtJ ENSMUSG00190015161
 protein coding gene Chr8:80508776-80515722 (+)
NZO/HlLtJ ENSMUSG00225040283
 protein coding gene Chr8:93543698-93550781 (+)
PWK/PhJ ENSLUMG00010028225
 protein coding gene Chr8:80186688-80193726 (+)
SPRET/EiJ ENSMSPG00010025373
 protein coding gene Chr8:82099079-82106193 (+)
WSB/EiJ ENSIUOG00005018323
 protein coding gene Chr8:81246391-81253338 (+)



Homology
more
  • Human Ortholog
    FBXW9, F-box and WD repeat domain containing 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXW9, F-box and WD repeat domain containing 9
  • Synonyms
    Fbw9, MEC-15
  • Links
    NCBI Gene ID: 84261
    UniProt: Q5XUX1

  • Chr Location
    19p13.13; chr19:12688053-12696649 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    43 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    616
  • Tissues
    18
  • cDNA Data
    50
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68628 NCBI Gene Model | MGI Sequence Detail 7003 C57BL/6J ±  kb
    transcript NM_026791 RefSeq | MGI Sequence Detail 1866 C57BL/6  
    polypeptide NP_081067 RefSeq | MGI Sequence Detail 458 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 51
      cDNA 51

      Microarray probesets 5
    References
    more
    • Summaries
      All 67
      Developmental Gene Expression 1
      Phenotypes 43
    • Earliest
      J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory