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Gdpd3 Gene Detail
Summary
  • Symbol
    Gdpd3
  • Name
    glycerophosphodiester phosphodiesterase domain containing 3
  • Synonyms
    1110015E22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915866
    NCBI Gene: 68616
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126766414-126775645 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.25 cM, cytoband F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    9 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915866
protein coding gene Chr7:126766334-126775649 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032996
protein coding gene Chr7:131062103-131074009 (+)
A/J MGP_AJ_G0032979
protein coding gene Chr7:127592114-127601394 (+)
AKR/J MGP_AKRJ_G0032911
protein coding gene Chr7:130822590-130835150 (+)
BALB/cJ MGP_BALBcJ_G0032984
protein coding gene Chr7:127252598-127262913 (+)
C3H/HeJ MGP_C3HHeJ_G0032694
protein coding gene Chr7:130762706-130772842 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033490
protein coding gene Chr7:136159093-136168406 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030462
protein coding gene Chr7:128784301-128793774 (+)
CAST/EiJ MGP_CASTEiJ_G0032023
protein coding gene Chr7:122545595-122559723 (+)
CBA/J MGP_CBAJ_G0032667
protein coding gene Chr7:140742512-140751833 (+)
DBA/2J MGP_DBA2J_G0032819
protein coding gene Chr7:125565873-125575182 (+)
FVB/NJ MGP_FVBNJ_G0032772
protein coding gene Chr7:125412842-125422330 (+)
LP/J MGP_LPJ_G0032913
protein coding gene Chr7:132533418-132544375 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032804
protein coding gene Chr7:141923845-141933124 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033509
protein coding gene Chr7:129831959-129841237 (+)
PWK/PhJ MGP_PWKPhJ_G0031730
protein coding gene Chr7:118560603-118570120 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031576
protein coding gene Chr7:116682847-116692216 (+)
WSB/EiJ MGP_WSBEiJ_G0032135
protein coding gene Chr7:130812637-130821912 (+)



Homology
more
  • Human Ortholog
    GDPD3, glycerophosphodiester phosphodiesterase domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GDPD3, glycerophosphodiester phosphodiesterase domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GDE7
  • Links
    NCBI Gene ID: 79153
    neXtProt AC: NX_Q7L5L3
    UniProt: Q7L5L3

  • Chr Location
    16p11.2; chr16:30104810-30113557 (-)  GRCh38.p7

Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    21 phenotype references
Mice homozygous for an ENU-induced allele exhibit normal blood lymphocyte populations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68616 NCBI Gene Model | MGI Sequence Detail 9232 C57BL/6J ±  kb
transcript NM_024228 RefSeq | MGI Sequence Detail 1081 C57BL/6  
polypeptide Q99LY2 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 3
References
more
  • Summaries
    All 46
    Developmental Gene Expression 1
    Diseases 3
    Gene Ontology 4
    Phenotypes 21
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:271893 Antoine MW, et al., Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models. Neuron. 2019 Feb 20;101(4):648-661.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory