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Caly Gene Detail
Summary
  • Symbol
    Caly
  • Name
    calcyon neuron-specific vesicular protein
  • Synonyms
    0710001P07Rik, 1110004A22Rik, Calcyon, Drd1ip
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915816
    NCBI Gene: 68566
  • Gene Overview
    MyGene.info: CALY
Location & Maps
more
  • Sequence Map
    Chr7:140069880-140082548 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      12669 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 85.07 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CALY, calcyon neuron specific vesicular protein
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CALY, calcyon neuron specific vesicular protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DRD1IP, NSG3
  • Links
    NCBI Gene ID: 50632
    neXtProt AC: NX_Q9NYX4

  • Chr Location
    10q26.3; chr10:133324072-133336971 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Radiation induced
    1
  • Targeted
    5
  • Transgenic
    1
  • Genomic Mutations
    1 involving Caly
  • Incidental Mutations
    CvDC
Neurons in homozygous null mice have defects in clathrin-mediated endocytosis (CME) that manifests as an absence of long term depression in post-synaptic currents of the hippocampus.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    199
  • Tissues
    28
  • cDNA Data
    16
  • Literature Summary
    2
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000060573 VEGA Gene Model | MGI Sequence Detail 12669 C57BL/6J ±  kb
transcript OTTMUST00000148179 VEGA | MGI Sequence Detail 1029 Not Applicable  
polypeptide OTTMUSP00000077057 VEGA | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    55 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004987 neuron-specific vesicular protein calcyon
  • InterPro Domains
    IPR009431 Calcyon neuron-specific vesicular protein
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
Other
Accession IDs
less
MGI:1923521
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:197462 Dillman AA, et al., mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci. 2013 Apr;16(4):499-506
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory