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Caly
Gene Detail
 Symbol
Name
ID
Caly
calcyon neuron-specific vesicular protein
MGI:1915816
Synonyms 0710001P07Rik, 1110004A22Rik, Calcyon, Drd1ip
Feature Type protein coding gene
Genetic Map
Chromosome 7
85.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:140069880-140082548 bp, - strand
From NCBI annotation of GRCm38

  12669 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: neuron specific protein/calcyon
Gene Tree: Caly

Human
homologs
Human Homolog CALY, calcyon neuron-specific vesicular protein
NCBI Gene ID 50632
neXtProt AC  NX_Q9NYX4
Human Synonyms  DRD1IP, NSG3
Human Chr (Location)  10q26.3; chr10:133325424-133336971 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
 
Neurons in homozygous null mice have defects in clathrin-mediated endocytosis (CME) that manifests as an absence of long term depression in post-synaptic currents of the hippocampus.
 
Interactions
Caly interacts with 67 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process clathrin coat assembly, dopamine receptor signaling pathway, ...
Component cytoplasmic vesicle, integral component of membrane, ...
Function clathrin light chain binding, protein complex binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (199)    Tissues (28)    Images (24)
Theiler Stages: 23
Assay TypeResults
RNA in situ 199
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000025468 (Evidence)
Entrez Gene68566 (Evidence)
UniGene44241
DFCITC1584185, TC1592222, TC1592329
DoTSDT.101146574, DT.101360351, DT.527742, DT.94289218
NIA Mouse Gene IndexU029418
Consensus CDS ProjectCCDS21962.1
International Mouse Knockout Project StatusCaly
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 68566 NCBI Gene Model | MGI Sequence Detail 12669 C57BL/6J ±  kb
transcript NM_001190386 RefSeq | MGI Sequence Detail 1262 C57BL/6 
polypeptide Q9DCA7 UniProt | EBI | MGI Sequence Detail 226 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(12) UniProt(1)
Polymorphisms SNPs within 2kb(55 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009431 Calcyon neuron-specific vesicular protein
Protein Ontology PR:000004987 neuron-specific vesicular protein calcyon
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:197462 Dillman AA, et al., mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci. 2013 Apr;16(4):499-506
All references(32)
Other
accession IDs
MGI:1923521

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory