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Dpm3 Gene Detail
Summary
  • Symbol
    Dpm3
  • Name
    dolichyl-phosphate mannosyltransferase polypeptide 3
  • Synonyms
    1110001H19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915813
    NCBI Gene: 68563
  • Gene Overview
    MyGene.info: DPM3
Location & Maps
more
  • Sequence Map
    Chr3:89259358-89267079 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7722 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 39.03 cM, cytoband F2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    DPM3, dolichyl-phosphate mannosyltransferase subunit 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DPM3, dolichyl-phosphate mannosyltransferase subunit 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CDG1O
  • Links
    NCBI Gene ID: 54344
    neXtProt AC: NX_Q9P2X0

  • Chr Location
    1q22; chr1:155139891-155140520 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human DPM3 associations

Human Disease Mouse Models
       Congenital Disorder of Glycosylation, Type Io; CDG1O   OMIM: 612937
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    22
  • Chemically induced (other)
    1
  • Gene trapped
    18
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Dpm3
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022265 VEGA Gene Model | MGI Sequence Detail 7722 C57BL/6J ±  kb
transcript OTTMUST00000053018 VEGA | MGI Sequence Detail 827 Not Applicable  
polypeptide OTTMUSP00000025186 VEGA | MGI Sequence Detail 92 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    14 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000006658 dolichol-phosphate mannosyltransferase subunit 3
  • InterPro Domains
    IPR013174 Dolichol-phosphate mannosyltransferase subunit 3
Molecular
Reagents
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  • All nucleic 38
    cDNA 37
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139935
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory