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Smim6 Gene Detail
Summary
  • Symbol
    Smim6
  • Name
    small integral membrane protein 6
  • Synonyms
    1110017F19Rik, ELN, endoregulin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915778
    NCBI Gene: 68528
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:115912017-115913917 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.91 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915778
protein coding gene Chr11:115912017-115913920 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019406
protein coding gene Chr11:119988565-119990467 (+)
A/J MGP_AJ_G0019375
protein coding gene Chr11:114739910-114741848 (+)
AKR/J MGP_AKRJ_G0019345
protein coding gene Chr11:118170241-118172143 (+)
BALB/cJ MGP_BALBcJ_G0019349
protein coding gene Chr11:115155886-115157734 (+)
C3H/HeJ MGP_C3HHeJ_G0019155
protein coding gene Chr11:118510919-118513342 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019799
protein coding gene Chr11:123646441-123649877 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017422
protein coding gene Chr11:111765231-111767119 (+)
CAST/EiJ MGP_CASTEiJ_G0018710
protein coding gene Chr11:119856250-119859602 (+)
CBA/J MGP_CBAJ_G0019127
protein coding gene Chr11:128542905-128544774 (+)
DBA/2J MGP_DBA2J_G0019238
protein coding gene Chr11:114162997-114164877 (+)
FVB/NJ MGP_FVBNJ_G0019230
protein coding gene Chr11:113671977-113673960 (+)
LP/J MGP_LPJ_G0019308
protein coding gene Chr11:120368779-120370682 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019263
protein coding gene Chr11:127654311-127657116 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019837
protein coding gene Chr11:118820058-118822622 (+)
PWK/PhJ MGP_PWKPhJ_G0018474
protein coding gene Chr11:115480484-115482324 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018267
protein coding gene Chr11:118568068-118569950 (+)
WSB/EiJ MGP_WSBEiJ_G0018762
protein coding gene Chr11:118784927-118786752 (+)



Homology
more
  • Human Ortholog
    SMIM6, small integral membrane protein 6
  • Human Ortholog
    SMIM6, small integral membrane protein 6
    Orthology source: HGNC
  • Synonyms
    C17orf110, ELN
  • Links
    NCBI Gene ID: 100130933
    neXtProt AC: NX_P0DI80
    UniProt: P0DI80

  • Chr Location
    chr17:75644805-75647977 (+)  GRCh38.p7

  • HCOP
    human homology predictions: SMIM6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68528 NCBI Gene Model | MGI Sequence Detail 1901 C57BL/6J ±  kb
transcript NM_001162998 RefSeq | MGI Sequence Detail 975 C57BL/6  
polypeptide NP_001156470 RefSeq | MGI Sequence Detail 56 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:260257 Anderson DM, et al., Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides. Sci Signal. 2016 Dec 6;9(457):ra119

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory