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Ucma Gene Detail
Summary
  • Symbol
    Ucma
  • Name
    upper zone of growth plate and cartilage matrix associated
  • Synonyms
    1110017I16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915777
    NCBI Gene: 68527
Location & Maps
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  • Genetic Map
    Chromosome 2, 3.11 cM
  • Mapping Data
    2 experiments
Homology
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  • Human Ortholog
    UCMA, upper zone of growth plate and cartilage matrix associated
  • Vertebrate Orthologs
    9
  • Human Ortholog
    UCMA, upper zone of growth plate and cartilage matrix associated
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10orf49, GRP, GRP/UCMA
  • Links
    NCBI Gene ID: 221044
    neXtProt AC: NX_Q8WVF2

  • Chr Location
    10p13; chr10:13221766-13234328 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 12272
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: UCMA
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
  • All Mutations and Alleles
    17
  • Gene trapped
    15
  • Targeted
    2
  • Incidental Mutations
    APF , CvDC
Mice homozygous for a knock-out allele exhibit normal skeleton phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010819 VEGA Gene Model | MGI Sequence Detail 9621 C57BL/6J ±  kb
transcript OTTMUST00000025301 VEGA | MGI Sequence Detail 847 Not Applicable  
polypeptide OTTMUSP00000011600 VEGA | MGI Sequence Detail 138 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    91 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
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  • All nucleic 9
    cDNA 7
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
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MGI:2139312
References
more
  • Summaries
    All 33
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:191689 Gross S, et al., Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice. PLoS One. 2012;7(8):e43553

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory