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Mrpl53 Gene Detail
Summary
  • Symbol
    Mrpl53
  • Name
    mitochondrial ribosomal protein L53
  • Synonyms
    1110007K17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915749
    NCBI Gene: 68499
Location & Maps
more
  • Genetic Map
    Chromosome 6, 35.94 cM, cytoband D1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MRPL53, mitochondrial ribosomal protein L53
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MRPL53, mitochondrial ribosomal protein L53
    Orthology source: HGNC, HomoloGene
  • Synonyms
    L53MT
  • Links
    NCBI Gene ID: 116540
    neXtProt AC: NX_Q96EL3

  • Chr Location
    2p13.1; chr2:74471958-74472815 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Mrpl53
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057884 VEGA Gene Model | MGI Sequence Detail 900 C57BL/6J ±  kb
transcript OTTMUST00000142140 VEGA | MGI Sequence Detail 695 Not Applicable  
polypeptide OTTMUSP00000074201 VEGA | MGI Sequence Detail 118 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    9 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010614 39S ribosomal protein L53, mitochondrial
  • InterPro Domains
    IPR019716 Ribosomal protein L53, mitochondrial
Molecular
Reagents
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  • All nucleic 71
    cDNA 71

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory