About   Help   FAQ
Ndufaf4
Gene Detail
Symbol

Name
ID
Ndufaf4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
MGI:1915743
Synonyms
1110007M04Rik, 3000003G13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
10.52 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:24898083-24905001 bp, + strand
From VEGA annotation of GRCm38

  6919 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40928  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NDUFAF4
Gene Tree: Ndufaf4

Human
homologs
NDUFAF4, NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 29078
neXtProt AC: NX_Q9P032

Human Synonyms: bA22L21.1, C6orf66, HRPAP20, HSPC125, My013

Human Chr (Location): 6q16.1; chr6:96889311-96897891 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFAF4

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from CvDC )
Interactions
Ndufaf4 interacts with 321 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process mitochondrial respiratory chain complex I assembly, NADH dehydrogenase complex assembly, ...
Component mitochondrial membrane, mitochondrion
Function calmodulin binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (90)    Tissues (10)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 90
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufaf4 ; ZFIN ndufaf4    NEW 
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000004822 (Evidence)
Ensembl Gene Model ENSMUSG00000028261 (Evidence)
Entrez Gene 68493 (Evidence)
DFCI TC1582590, TC1638046
DoTS DT.101374205, DT.94245666
NIA Mouse Gene Index U004136
Consensus CDS Project CCDS18007.1
International Mouse Phenotyping Consortium Status Ndufaf4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004822 VEGA Gene Model | MGI Sequence Detail 6919 C57BL/6J ±  kb
transcript OTTMUST00000010805 VEGA | MGI Sequence Detail 3632 Not Applicable 
polypeptide OTTMUSP00000005078 VEGA | MGI Sequence Detail 173 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(91 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009622 Uncharacterised protein family UPF0240
Protein Ontology PR:000008754 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201547 Schlehe JS, et al., The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress. Neurobiol Dis. 2013 Oct;58:57-67
All references(32)
Other
accession IDs
MGI:1914882, MGI:2140562

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory