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Mpzl1 Gene Detail
Summary
  • Symbol
    Mpzl1
  • Name
    myelin protein zero-like 1
  • Synonyms
    1110007A10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915731
    NCBI Gene: 68481
  • Gene Overview
    MyGene.info: MPZL1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:165592240-165634538 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 72.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    424 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915731
protein coding gene Chr1:165592181-165634560 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016695
protein coding gene Chr1:171083798-171127539 (-)
A/J MGP_AJ_G0016676
protein coding gene Chr1:164100282-164143266 (-)
AKR/J MGP_AKRJ_G0016642
protein coding gene Chr1:169064308-169107379 (-)
BALB/cJ MGP_BALBcJ_G0016637
protein coding gene Chr1:164598656-164639800 (-)
C3H/HeJ MGP_C3HHeJ_G0016461
protein coding gene Chr1:169280421-169330589 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017098
protein coding gene Chr1:176819205-176865226 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014807
protein coding gene Chr1:156000042-156041576 (-)
CAST/EiJ MGP_CASTEiJ_G0016041
protein coding gene Chr1:168908240-168950927 (-)
CBA/J MGP_CBAJ_G0016436
protein coding gene Chr1:183090202-183136313 (-)
DBA/2J MGP_DBA2J_G0016542
protein coding gene Chr1:162986148-163026269 (-)
FVB/NJ MGP_FVBNJ_G0016540
protein coding gene Chr1:161424072-161466427 (-)
LP/J MGP_LPJ_G0016613
protein coding gene Chr1:172142627-172189431 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016565
protein coding gene Chr1:190603082-190646210 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017134
protein coding gene Chr1:168923787-168969017 (-)
PWK/PhJ MGP_PWKPhJ_G0015827
protein coding gene Chr1:162188789-162231556 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015614
protein coding gene Chr1:167770615-167821347 (-)
WSB/EiJ MGP_WSBEiJ_G0016103
protein coding gene Chr1:169078679-169121236 (-)



Homology
more
  • Human Ortholog
    MPZL1, myelin protein zero like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MPZL1, myelin protein zero like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MPZL1b, PZR, PZR1b, PZRa, PZRb
  • Links
    NCBI Gene ID: 9019
    neXtProt AC: NX_O95297
    UniProt: O95297

  • Chr Location
    1q24.2; chr1:167721950-167791919 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2939
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MPZL1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026566 Ensembl Gene Model | MGI Sequence Detail 42299 C57BL/6J ±  kb
transcript ENSMUST00000111435 Ensembl | MGI Sequence Detail 2285 Not Applicable  
polypeptide ENSMUSP00000107062 Ensembl | MGI Sequence Detail 270 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 156
    cDNA 154
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory