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Tmem126b Gene Detail
Summary
  • Symbol
    Tmem126b
  • Name
    transmembrane protein 126B
  • Synonyms
    1110001A23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915722
    NCBI Gene: 68472
  • Gene Overview
    MyGene.info: TMEM126B
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:90468833-90475995 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 50.60 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915722
protein coding gene Chr7:90467438-90476001 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032509
protein coding gene Chr7:92897881-92905644 (-)
A/J MGP_AJ_G0032483
protein coding gene Chr7:90654186-90661968 (-)
AKR/J MGP_AKRJ_G0032419
protein coding gene Chr7:92779385-92787185 (-)
BALB/cJ MGP_BALBcJ_G0032494
protein coding gene Chr7:90301393-90309185 (-)
C3H/HeJ MGP_C3HHeJ_G0032209
protein coding gene Chr7:93163519-93171306 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032992
protein coding gene Chr7:96524656-96532448 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029987
protein coding gene Chr7:93534032-93542024 (-)
CAST/EiJ MGP_CASTEiJ_G0031536
protein coding gene Chr7:84602954-84610808 (-)
CBA/J MGP_CBAJ_G0032176
protein coding gene Chr7:99735323-99743114 (-)
DBA/2J MGP_DBA2J_G0032328
protein coding gene Chr7:89089053-89096875 (-)
FVB/NJ MGP_FVBNJ_G0032284
protein coding gene Chr7:88956728-88965209 (-)
LP/J MGP_LPJ_G0032417
protein coding gene Chr7:94167860-94177096 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032318
protein coding gene Chr7:100742590-100751154 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033014
protein coding gene Chr7:92057731-92065521 (-)
PWK/PhJ MGP_PWKPhJ_G0031254
protein coding gene Chr7:82125249-82133281 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031097
protein coding gene Chr7:79379746-79387400 (-)
WSB/EiJ MGP_WSBEiJ_G0031653
protein coding gene Chr7:92732593-92740417 (-)



Homology
more
  • Human Ortholog
    TMEM126B, transmembrane protein 126B
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TMEM126B, transmembrane protein 126B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HT007
  • Links
    NCBI Gene ID: 55863
    neXtProt AC: NX_Q8IUX1
    UniProt: Q8IUX1

  • Chr Location
    11q14.1; chr11:85628573-85636539 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human TMEM126B associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    29 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    3
  • Targeted
    2
  • Genomic Mutations
    4 involving Tmem126b
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68472 NCBI Gene Model | MGI Sequence Detail 7163 C57BL/6J ±  kb
transcript NM_026734 RefSeq | MGI Sequence Detail 858 C57BL/6  
polypeptide Q9D1R1 UniProt | EBI | MGI Sequence Detail 230 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 3
References
more
  • Summaries
    All 51
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 29
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:204566 Gendrel AV, et al., Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory