About   Help   FAQ
Dhrs7c Gene Detail
Summary
  • Symbol
    Dhrs7c
  • Name
    dehydrogenase/reductase (SDR family) member 7C
  • Synonyms
    1110001P11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915710
    NCBI Gene: 68460
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:67798271-67816002 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 41.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    232 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915710
protein coding gene Chr11:67798187-67816002 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018495
protein coding gene Chr11:68117416-68135238 (+)
A/J MGP_AJ_G0018464
protein coding gene Chr11:65571424-65589228 (+)
AKR/J MGP_AKRJ_G0018433
protein coding gene Chr11:67530458-67548280 (+)
BALB/cJ MGP_BALBcJ_G0018435
protein coding gene Chr11:65850641-65868498 (+)
C3H/HeJ MGP_C3HHeJ_G0018248
protein coding gene Chr11:67542629-67560449 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018887
protein coding gene Chr11:70195149-70212963 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016531
protein coding gene Chr11:62523023-62540800 (+)
CAST/EiJ MGP_CASTEiJ_G0017804
protein coding gene Chr11:67766759-67784677 (+)
CBA/J MGP_CBAJ_G0018222
protein coding gene Chr11:73296255-73315290 (+)
DBA/2J MGP_DBA2J_G0018331
protein coding gene Chr11:65172512-65190335 (+)
FVB/NJ MGP_FVBNJ_G0018321
protein coding gene Chr11:64781068-64799486 (+)
LP/J MGP_LPJ_G0018402
protein coding gene Chr11:68690907-68710113 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018344
protein coding gene Chr11:74049063-74067150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018928
protein coding gene Chr11:67778309-67796162 (+)
PWK/PhJ MGP_PWKPhJ_G0017579
protein coding gene Chr11:65787968-65806328 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017367
protein coding gene Chr11:67608020-67626649 (+)
WSB/EiJ MGP_WSBEiJ_G0017857
protein coding gene Chr11:67384771-67402718 (+)



Homology
more
  • Human Ortholog
    DHRS7C, dehydrogenase/reductase 7C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHRS7C, dehydrogenase/reductase 7C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SDR32C2
  • Links
    NCBI Gene ID: 201140
    neXtProt AC: NX_A6NNS2
    UniProt: A6NNS2

  • Chr Location
    17p13.1; chr17:9771434-9791297 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19108
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DHRS7C
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Transgenic
    1
  • Genomic Mutations
    1 involving Dhrs7c
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68460 NCBI Gene Model | MGI Sequence Detail 17732 C57BL/6J ±  kb
transcript NM_001013013 RefSeq | MGI Sequence Detail 1129 C57BL/6  
polypeptide Q8CHS7 UniProt | EBI | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144071
References
more
  • Summaries
    All 29
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:260197 Ruiz A, et al., Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance. Sci Rep. 2018 Jan 12;8(1):636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory