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Gpihbp1
Gene Detail
 Symbol
Name
ID
Gpihbp1
GPI-anchored HDL-binding protein 1
MGI:1915703
Synonyms 1110002J19Rik, GPI-HBP1
Feature Type protein coding gene
Genetic Map
Chromosome 15
34.59 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:75596628-75599481 bp, + strand
From VEGA annotation of GRCm38

  2854 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136164  Vertebrate Homology Class
1 mouse; 1 rat

Gene Tree: Gpihbp1

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Radiation induced(1) Targeted(5)
Genomic Mutations involving Gpihbp1 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit milky plasma due to increased triglyceride and cholesterol levels.
 
Interactions
Gpihbp1 interacts with 30 markers (Mir22, Mir26a-1, Mir26a-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (32 annotations)
Process cholesterol homeostasis, intracellular protein transport, ...
Component anchored component of membrane, anchored component of plasma membrane, ...
Function chylomicron binding, high-density lipoprotein particle binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(49)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(49)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000045187 (Evidence)
Ensembl Gene ModelENSMUSG00000022579 (Evidence)
Entrez Gene68453 (Evidence)
UniGene46367
DFCITC1581997, TC1593273
DoTSDT.492649, DT.94181165
NIA Mouse Gene IndexU016347
Consensus CDS ProjectCCDS27545.1
International Mouse Knockout Project StatusGpihbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045187 VEGA Gene Model | MGI Sequence Detail 2854 C57BL/6J ±  kb
transcript OTTMUST00000118729 VEGA | MGI Sequence Detail 825 Not Applicable 
polypeptide OTTMUSP00000066253 VEGA | MGI Sequence Detail 228 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001526 CD59 antigen
InterPro IPR018363 CD59 antigen, conserved site
InterPro IPR016054 Ly-6 antigen / uPA receptor -like
Protein Ontology PR:000008176 glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:195963 Weinstein MM, et al., Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):230-5
All references(43)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory