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Gpihbp1
Gene Detail
Symbol

Name
ID
Gpihbp1
GPI-anchored HDL-binding protein 1
MGI:1915703
Synonyms
1110002J19Rik, GPI-HBP1
Feature Type
protein coding gene
Genetic Map
Chromosome 15
34.59 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:75596628-75599481 bp, + strand
From VEGA annotation of GRCm38

  2854 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136164  Vertebrate Homology Class
1 mouse; 1 rat

HCOP human homology predictions: GPIHBP1
Gene Tree: Gpihbp1

Human
homologs
GPIHBP1, glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
Orthology source: HGNC

IDs:
NCBI Gene ID: 338328
neXtProt AC: NX_Q8IV16

Human Synonyms: GPI-HBP1, HYPL1D

Human Chr (Location): 8q24.3; chr8:143213193-143217170 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human GPIHBP1

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Radiation induced(1) Targeted(5)
Genomic Mutations involving Gpihbp1 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit milky plasma due to increased triglyceride and cholesterol levels.
 
Phenotype Images(2)
Interactions
Gpihbp1 interacts with 30 markers (Mir22, Mir26a-1, Mir26a-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(49)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(49)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000045187 (Evidence)
Ensembl Gene Model ENSMUSG00000022579 (Evidence)
Entrez Gene 68453 (Evidence)
UniGene 46367
DFCI TC1581997, TC1593273
DoTS DT.94181165, DT.492649
NIA Mouse Gene Index U016347
Consensus CDS Project CCDS27545.1
International Mouse Phenotyping Consortium Status Gpihbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045187 VEGA Gene Model | MGI Sequence Detail 2854 C57BL/6J ±  kb
transcript OTTMUST00000118729 VEGA | MGI Sequence Detail 825 Not Applicable 
polypeptide OTTMUSP00000066253 VEGA | MGI Sequence Detail 228 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001526 CD59 antigen
InterPro IPR018363 CD59 antigen, conserved site
InterPro IPR016054 Ly-6 antigen / uPA receptor -like
Protein Ontology PR:000008176 glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:216170 Jiang H, et al., High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis. J Lipid Res. 2014 Oct;55(10):2156-66
All references(44)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory