Slc39a13 MGI Mouse Gene Detail - MGI:1915677 - solute carrier family 39 (metal ion transporter), member 13

Symbol

Slc39a13
Name

solute carrier family 39 (metal ion transporter), member 13
Synonyms

1100001L14Rik, ZIP13

Feature Type

protein coding gene
IDs

MGI:1915677
NCBI Gene: 68427
Alliance

genome feature page
Transcription Start Sites

3 TSS

Sequence Map

Chr2:90892136-90900754 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 50.44 cM, cytoband E1
Mapping Data

3 experiments

SNPs within 2kb

246 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915677	protein coding gene	Chr2:90892136-90900762 (-)
129S1/SvImJ	ENSMUSG00200052241	protein coding gene	Chr2:87807678-87815540 (-)
A/J	ENSMUSG00195049291	protein coding gene	Chr2:87934288-87942150 (-)
AKR/J	ENSMUSG00220047439	protein coding gene	Chr2:87737401-87745265 (-)
BALB/cJ	ENSMUSG00180054797	protein coding gene	Chr2:87834494-87842357 (-)
C3H/HeJ	ENSMUSG00175053470	protein coding gene	Chr2:88103408-88111272 (-)
C57BL/6NJ	ENSMUSG00215051108	protein coding gene	Chr2:87934794-87942657 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023952	protein coding gene	Chr2:85186794-85195398 (-)
CAST/EiJ	ENSTCUG00005049764	protein coding gene	Chr2:87345006-87352231 (-)
CBA/J	ENSMUSG00210037138	protein coding gene	Chr2:88114558-88122421 (-)
DBA/2J	ENSMUSG00185056347	protein coding gene	Chr2:87830944-87838806 (-)
FVB/NJ	ENSMUSG00205043693	protein coding gene	Chr2:87127696-87135559 (-)
JF1/MsJ	ENSUMUG00000013328	protein coding gene	Chr2:87649631-87657473 (-)
LP/J	ENSMUSG00230036565	protein coding gene	Chr2:89581619-89589480 (-)
NOD/ShiLtJ	ENSMUSG00190047025	protein coding gene	Chr2:87909706-87917567 (-)
NZO/HlLtJ	ENSMUSG00225049814	protein coding gene	Chr2:97503245-97511106 (-)
PWK/PhJ	ENSLUMG00010046971	protein coding gene	Chr2:87638270-87646111 (-)
SPRET/EiJ	ENSMSPG00010051997	protein coding gene	Chr2:89593223-89603559 (-)
WSB/EiJ	ENSIUOG00005053172	protein coding gene	Chr2:87637523-87645383 (-)

Human Ortholog

SLC39A13, solute carrier family 39 member 13

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC39A13, solute carrier family 39 member 13
Synonyms

EDSSPD3, LZT-Hs9, SCDEDS, ZIP13
Links

HGNC:20859

NCBI Gene ID: 91252

UniProt: Q96H72
Chr Location

11p11.2; chr11:47407132-47416587 (+) GRCh38

MGI Vertebrate Homology

Slc39a13 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SLC39A13
Gene Tree

Slc39a13

Diseases

2 with human SLC39A13 associations

				Human Disease	Mouse Models
				Ehlers-Danlos syndrome IDs Ehlers-Danlos syndrome DOID:13359 DOID:14696 ICD10CM:Q79.6 ICD9CM:756.83 MESH:D004535 NCI:C34568 OMIM:PS130000 UMLS_CUI:C0013720
				Ehlers-Danlos syndrome spondylodysplastic type 3 IDs Ehlers-Danlos syndrome spondylodysplastic type 3 DOID:0080739 OMIM:612350

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

29 phenotypes from 1 allele in 1 genetic background
2 images
28 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

15
Chemically induced (other)

1
Endonuclease-mediated

4
Gene trapped

4
Radiation induced

1
Targeted

5
Genomic Mutations

4 involving Slc39a13
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

20 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for disruption of this gene display skeletal abnormalities and dental abnormalities.

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All GO Annotations

56
GO References

9

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

601
Tissues

2
cDNA Data

46
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN slc39a13

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All Sequences

79
RefSeq

29
UniProt

3
CCDS

CCDS16424.1, CCDS71095.1

Ensembl

ENSMUSG00000002105 (Evidence)
NCBI Gene

68427

			Length	Strain/Species	Flank
genomic	68427	NCBI Gene Model \| MGI Sequence Detail	8619	C57BL/6J	± kb
transcript	NM_001290765	RefSeq \| MGI Sequence Detail	2315	C57BL/6
polypeptide	Q8BZH0	UniProt \| EBI \| MGI Sequence Detail	361	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000015127 zinc transporter ZIP13

(term hierarchy)
InterPro Domains

IPR003689 Zinc/iron permease
GlyGen

Q8BZH0 1 site

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All nucleic 47

cDNA 46

Primer pair 1

Microarray probesets 3

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MGI:3035256

Summaries

All 61

Developmental Gene Expression 1

Gene Ontology 9

Phenotypes 28
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:389113 Guo S, et al., The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis. Adv Sci (Weinh). 2026 Apr;13(20):e16446

TSS for Slc39a13:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr25149	Chr2:90900647-90900691 (-)	85 bp
Tssr25148	Chr2:90900525-90900594 (-)	194 bp
Tssr25147	Chr2:90893461-90893470 (-)	7,288 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24