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Map1lc3a Gene Detail
Summary
  • Symbol
    Map1lc3a
  • Name
    microtubule-associated protein 1 light chain 3 alpha
  • Synonyms
    1010001H21Rik, 4922501H04Rik, LC3, LC3a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915661
    NCBI Gene: 66734
  • Gene Overview
    MyGene.info: MAP1LC3A
Location & Maps
more
  • Sequence Map
    Chr2:155276297-155278073 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1777 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 77.18 cM, cytoband H2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MAP1LC3A, microtubule associated protein 1 light chain 3 alpha
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MAP1LC3A, microtubule associated protein 1 light chain 3 alpha
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
  • Links
    NCBI Gene ID: 84557
    neXtProt AC: NX_Q9H492

  • Chr Location
    20q11.22; chr20:34546830-34560345 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016007 VEGA Gene Model | MGI Sequence Detail 1777 C57BL/6J ±  kb
transcript OTTMUST00000038114 VEGA | MGI Sequence Detail 1112 Not Applicable  
polypeptide OTTMUSP00000017090 VEGA | MGI Sequence Detail 121 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    27 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010119 microtubule-associated proteins 1A/1B light chain 3A
  • InterPro Domains
    IPR004241 Autophagy protein Atg8 ubiquitin-like
    IPR029071 Ubiquitin-related domain
Molecular
Reagents
less
  • All nucleic 139
    cDNA 135
    Primer pair 3
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913984
References
more
  • Summaries
    All 65
    Developmental Gene Expression 22
    Gene Ontology 12
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228212 Cinque L, et al., FGF signalling regulates bone growth through autophagy. Nature. 2015 Dec 10;528(7581):272-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory