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Map1lc3a Gene Detail
Summary
  • Symbol
    Map1lc3a
  • Name
    microtubule-associated protein 1 light chain 3 alpha
  • Synonyms
    1010001H21Rik, 4922501H04Rik, LC3, LC3a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915661
    NCBI Gene: 66734
  • Gene Overview
    MyGene.info: MAP1LC3A
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:155276364-155278073 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 77.18 cM, cytoband H2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915661
protein coding gene Chr2:155276297-155278073 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026731
protein coding gene Chr2:160085849-160087625 (+)
A/J MGP_AJ_G0026697
protein coding gene Chr2:153722060-153723836 (+)
AKR/J MGP_AKRJ_G0026668
protein coding gene Chr2:158183025-158184801 (+)
BALB/cJ MGP_BALBcJ_G0026706
protein coding gene Chr2:154025234-154027016 (+)
C3H/HeJ MGP_C3HHeJ_G0026449
protein coding gene Chr2:158542829-158544613 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027155
protein coding gene Chr2:164777241-164779017 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024525
protein coding gene Chr2:147227515-147229297 (+)
CAST/EiJ MGP_CASTEiJ_G0025910
protein coding gene Chr2:158845337-158847110 (+)
CBA/J MGP_CBAJ_G0026426
protein coding gene Chr2:170775411-170777197 (+)
DBA/2J MGP_DBA2J_G0026563
protein coding gene Chr2:152906123-152907899 (+)
FVB/NJ MGP_FVBNJ_G0026530
protein coding gene Chr2:151287136-151288891 (+)
LP/J MGP_LPJ_G0026668
protein coding gene Chr2:160228887-160230663 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026551
protein coding gene Chr2:174770049-174771830 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027211
protein coding gene Chr2:158071381-158073160 (+)
PWK/PhJ MGP_PWKPhJ_G0025644
protein coding gene Chr2:152405859-152407635 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025447
protein coding gene Chr2:157001534-157003309 (+)
WSB/EiJ MGP_WSBEiJ_G0025980
protein coding gene Chr2:158955714-158958583 (+)



Homology
more
  • Human Ortholog
    MAP1LC3A, microtubule associated protein 1 light chain 3 alpha
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MAP1LC3A, microtubule associated protein 1 light chain 3 alpha
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
  • Links
    NCBI Gene ID: 84557
    neXtProt AC: NX_Q9H492
    UniProt: Q9H492

  • Chr Location
    20q11.22; chr20:34546823-34560345 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66734 NCBI Gene Model | MGI Sequence Detail 1710 C57BL/6J ±  kb
transcript NM_025735 RefSeq | MGI Sequence Detail 1063 C57BL/6  
polypeptide Q91VR7 UniProt | EBI | MGI Sequence Detail 121 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 140
    cDNA 136
    Primer pair 3
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913984
References
more
  • Summaries
    All 99
    Developmental Gene Expression 31
    Gene Ontology 16
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:262835 Ke FFS, et al., Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK. Cell. 2018 May 17;173(5):1217-1230.e17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory