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Map1lc3a
Gene Detail
Symbol

Name
ID
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
MGI:1915661
Synonyms
1010001H21Rik, 4922501H04Rik, LC3, LC3a
Feature Type
protein coding gene
Genetic Map
Chromosome 2
77.18 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:155276297-155278073 bp, + strand
From VEGA annotation of GRCm38

  1777 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12021  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: microtubule-associated proteins 1 light chain 3A/3B
Gene Tree: Map1lc3a

Human
homologs
Human Homolog MAP1LC3A, microtubule-associated protein 1 light chain 3 alpha
NCBI Gene ID 84557
neXtProt AC  NX_Q9H492
Human Synonyms  ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
Human Chr (Location)  20q11.22; chr20:34546884-34560345 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Map1lc3a interacts with 57 markers (Mir15a, Mir17, Mir20b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process autophagic vacuole assembly, autophagy, ...
Component autophagic vacuole, autophagic vacuole membrane, ...
Function GABA receptor binding, microtubule binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (86)    Tissues (39)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 74
Western blot 12
cDNA source data(135)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(137) cDNA(135) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000016007 (Evidence)
Ensembl Gene ModelENSMUSG00000027602 (Evidence)
Entrez Gene66734 (Evidence)
UniGene196239
DFCITC1576095, TC1588601, TC1746599
DoTSDT.535785
NIA Mouse Gene IndexU002701
Consensus CDS ProjectCCDS16945.1
International Mouse Knockout Project StatusMap1lc3a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016007 VEGA Gene Model | MGI Sequence Detail 1777 C57BL/6J ±  kb
transcript OTTMUST00000038114 VEGA | MGI Sequence Detail 1112 Not Applicable 
polypeptide OTTMUSP00000017090 VEGA | MGI Sequence Detail 121 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(3) UniProt(1)
Polymorphisms
SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004241 Autophagy protein Atg8 ubiquitin-like
Protein Ontology PR:000010119 microtubule-associated proteins 1A/1B light chain 3A
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203690 Martinez-Lopez N, et al., Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development. EMBO Rep. 2013 Sep;14(9):795-803
All references(58)
Other
accession IDs
MGI:1913984

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory