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Ndufs3 Gene Detail
Summary
  • Symbol
    Ndufs3
  • Name
    NADH:ubiquinone oxidoreductase core subunit S3
  • Synonyms
    0610010M09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915599
    NCBI Gene: 68349
  • Gene Overview
    MyGene.info: NDUFS3
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr2:90894634-90904827 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10194 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 50.44 cM, cytoband E1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    NDUFS3, NADH:ubiquinone oxidoreductase core subunit S3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NDUFS3, NADH:ubiquinone oxidoreductase core subunit S3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CI-30
  • Links
    NCBI Gene ID: 4722
    neXtProt AC: NX_O75489
    UniProt: O75489

  • Chr Location
    11p11.2; chr11:47579010-47584563 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human NDUFS3 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000014317 VEGA Gene Model | MGI Sequence Detail 10194 C57BL/6J ±  kb
    transcript OTTMUST00000033776 VEGA | MGI Sequence Detail 1046 Not Applicable  
    polypeptide OTTMUSP00000015131 VEGA | MGI Sequence Detail 263 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      31 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000011098 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    • EC
    • InterPro Domains
      IPR010218 NADH dehydrogenase, subunit C
      IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit
      IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site
      IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily
    Molecular
    Reagents
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    • All nucleic 65
      cDNA 64
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:227263 Fabre PJ, et al., Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13964-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory