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Ift20 Gene Detail
Summary
  • Symbol
    Ift20
  • Name
    intraflagellar transport 20
  • Synonyms
    0610009H04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915585
    NCBI Gene: 55978
  • Gene Overview
    MyGene.info: IFT20
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78536436-78541473 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915585
protein coding gene Chr11:78536361-78541737 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018787
protein coding gene Chr11:79556228-79561606 (+)
A/J MGP_AJ_G0018753
protein coding gene Chr11:76508978-76516253 (+)
AKR/J MGP_AKRJ_G0018723
protein coding gene Chr11:78813413-78818781 (+)
BALB/cJ MGP_BALBcJ_G0018727
protein coding gene Chr11:76910711-76916070 (+)
C3H/HeJ MGP_C3HHeJ_G0018540
protein coding gene Chr11:78861429-78868708 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019178
protein coding gene Chr11:82025060-82032158 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016813
protein coding gene Chr11:73477207-73482893 (+)
CAST/EiJ MGP_CASTEiJ_G0018094
protein coding gene Chr11:79315275-79320655 (+)
CBA/J MGP_CBAJ_G0018511
protein coding gene Chr11:85640508-85645885 (+)
DBA/2J MGP_DBA2J_G0018619
protein coding gene Chr11:76081979-76087347 (+)
FVB/NJ MGP_FVBNJ_G0018609
protein coding gene Chr11:75672894-75678261 (+)
LP/J MGP_LPJ_G0018690
protein coding gene Chr11:80070010-80075375 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018635
protein coding gene Chr11:85997526-86002896 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019218
protein coding gene Chr11:79061688-79067052 (+)
PWK/PhJ MGP_PWKPhJ_G0017865
protein coding gene Chr11:76878550-76883954 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017656
protein coding gene Chr11:78676309-78681639 (+)
WSB/EiJ MGP_WSBEiJ_G0018147
protein coding gene Chr11:78892038-78897438 (+)



Homology
more
  • Human Ortholog
    IFT20, intraflagellar transport 20
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IFT20, intraflagellar transport 20
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 90410
    neXtProt AC: NX_Q8IY31
    UniProt: Q8IY31

  • Chr Location
    17q11.2; chr17:28328325-28335489 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 49559
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: IFT20
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 3 alleles in 3 genetic backgrounds
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation die before birth. Mice with conditional loss in renal collecting ducts lack primary cilia and develop renal cysts.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 55978 NCBI Gene Model | MGI Sequence Detail 5038 C57BL/6J ±  kb
transcript NM_018854 RefSeq | MGI Sequence Detail 1136 C57BL/6  
polypeptide Q61025 UniProt | EBI | MGI Sequence Detail 132 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    cDNA 115

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144373
References
more
  • Summaries
    All 67
    Developmental Gene Expression 2
    Gene Ontology 26
    Phenotypes 23
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265626 Zhang Z, et al., Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice. Mol Biol Cell. 2016 Sep 28;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory