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Sdhaf1
Gene Detail
Symbol

Name
ID
Sdhaf1
succinate dehydrogenase complex assembly factor 1
MGI:1915582
Synonyms
0610010E21Rik, Lyrm8
Feature Type
protein coding gene
Genetic Map
Chromosome 7
17.39 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:30321406-30323895 bp, - strand
From VEGA annotation of GRCm38

  2490 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:67970  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SDHAF1
Gene Tree: Sdhaf1

Human
homologs
SDHAF1, succinate dehydrogenase complex assembly factor 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 644096
neXtProt AC: NX_A6NFY7

Human Synonyms: LYRM8

Human Chr (Location): 19q13.12; chr19:35995188-35996318 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SDHAF1

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Interactions
Sdhaf1 interacts with 67 markers (Mir7-2, Mir7b, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process mitochondrial respiratory chain complex II assembly
Component mitochondrion
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(36)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: ZFIN sdhaf1    NEW 
Molecular
reagents
All nucleic(36) cDNA(36)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000022883 (Evidence)
Ensembl Gene Model ENSMUSG00000074211 (Evidence)
Entrez Gene 68332 (Evidence)
UniGene 6844
DFCI TC1584812, TC1601584
Consensus CDS Project CCDS39881.1
International Mouse Phenotyping Consortium Status Sdhaf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022883 VEGA Gene Model | MGI Sequence Detail 2490 C57BL/6J ±  kb
transcript OTTMUST00000055041 VEGA | MGI Sequence Detail 2490 Not Applicable 
polypeptide OTTMUSP00000026298 VEGA | MGI Sequence Detail 118 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008011 Complex 1 LYR protein
Protein Ontology PR:000030806 succinate dehydrogenase assembly factor 1, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(26)
Other
accession IDs
MGI:2141957, MGI:2142235

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory