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Tlcd1 Gene Detail
Summary
  • Symbol
    Tlcd1
  • Name
    TLC domain containing 1
  • Synonyms
    0610007A15Rik, 0610030G03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915572
    NCBI Gene: 68385
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78176716-78180820 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 46.74 cM, cytoband B5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915572
protein coding gene Chr11:78176711-78181909 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018766
protein coding gene Chr11:79158341-79163539 (+)
A/J MGP_AJ_G0018732
protein coding gene Chr11:76135498-76140696 (+)
AKR/J MGP_AKRJ_G0018702
protein coding gene Chr11:78440609-78445807 (+)
BALB/cJ MGP_BALBcJ_G0018706
protein coding gene Chr11:76544716-76549914 (+)
C3H/HeJ MGP_C3HHeJ_G0018519
protein coding gene Chr11:78481694-78486892 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019157
protein coding gene Chr11:81629959-81635157 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016792
protein coding gene Chr11:73109476-73114713 (+)
CAST/EiJ MGP_CASTEiJ_G0018073
protein coding gene Chr11:78918831-78924022 (+)
CBA/J MGP_CBAJ_G0018489
protein coding gene Chr11:85191877-85197075 (+)
DBA/2J MGP_DBA2J_G0018598
protein coding gene Chr11:75717644-75722842 (+)
FVB/NJ MGP_FVBNJ_G0018588
protein coding gene Chr11:75305494-75310692 (+)
LP/J MGP_LPJ_G0018669
protein coding gene Chr11:79694081-79699279 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018614
protein coding gene Chr11:85614054-85619252 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019197
protein coding gene Chr11:78683453-78688651 (+)
PWK/PhJ MGP_PWKPhJ_G0017844
protein coding gene Chr11:76499341-76504534 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017635
protein coding gene Chr11:78291224-78297325 (+)
WSB/EiJ MGP_WSBEiJ_G0018126
protein coding gene Chr11:78497020-78502218 (+)



Homology
more
  • Human Ortholog
    TLCD1, TLC domain containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TLCD1, TLC domain containing 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 116238
    neXtProt AC: NX_Q96CP7
    UniProt: Q96CP7

  • Chr Location
    17q11.2; chr17:28724348-28727930 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    3
  • Genomic Mutations
    2 involving Tlcd1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68385 NCBI Gene Model | MGI Sequence Detail 4105 C57BL/6J ±  kb
transcript NM_001291236 RefSeq | MGI Sequence Detail 1619 C57BL/6  
polypeptide Q99JT6 UniProt | EBI | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 6
Other
Accession IDs
less
MGI:1915635, MGI:2144045, MGI:2144375
References
more
  • Summaries
    All 39
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory