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Stt3b Gene Detail
Summary
  • Symbol
    Stt3b
  • Name
    STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
  • Synonyms
    1300006C19Rik, Simp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915542
    NCBI Gene: 68292
  • Gene Overview
    MyGene.info: STT3B
Location & Maps
more
  • Sequence Map
    Chr9:115242607-115310421 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      67815 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 67.71 cM, cytoband F3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    STT3B, STT3B, catalytic subunit of the oligosaccharyltransferase complex
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STT3B, STT3B, catalytic subunit of the oligosaccharyltransferase complex
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDG1X, SIMP, STT3-B
  • Links
    NCBI Gene ID: 201595
    neXtProt AC: NX_Q8TCJ2

  • Chr Location
    3p23; chr3:31532501-31637622 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 7387
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: STT3B
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human STT3B associations

Human Disease Mouse Models
       Congenital Disorder of Glycosylation, Type IX; CDG1X   OMIM: 615597
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032437 Ensembl Gene Model | MGI Sequence Detail 67815 C57BL/6J ±  kb
transcript ENSMUST00000035010 Ensembl | MGI Sequence Detail 4195 Not Applicable  
polypeptide ENSMUSP00000035010 Ensembl | MGI Sequence Detail 823 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    678 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR003674 Oligosaccharyl transferase, STT3 subunit
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:165993 Lee JH, et al., Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell. 2010 Jun 25;141(7):1146-58

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory