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Dnaaf1
Gene Detail
Symbol

Name
ID
Dnaaf1
dynein, axonemal assembly factor 1
MGI:1915520
Synonyms
4930457P18Rik, Lrrc50
Feature Type
protein coding gene
Genetic Map
Chromosome 8
67.98 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:119575235-119598454 bp, + strand
From VEGA annotation of GRCm38

  23220 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog

HCOP human homology predictions: DNAAF1
Gene Tree: Dnaaf1

Human
homologs
DNAAF1, dynein, axonemal, assembly factor 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 123872
neXtProt AC: NX_Q8NEP3

Human Synonyms: CILD13, LRRC50, ODA7

Human Chr (Location): 16q24.1; chr16:84145260-84177918 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DNAAF1

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from APF , CvDC )
Interactions
Dnaaf1 interacts with 98 markers (Mir1b, Mir17, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process axonemal dynein complex assembly, cilium morphogenesis, ...
Component axoneme, cell projection, ...
Function dynein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (7)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 7
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000031110 (Evidence)
Ensembl Gene Model ENSMUSG00000031831 (Evidence)
Entrez Gene 68270 (Evidence)
Consensus CDS Project CCDS22709.1
International Mouse Phenotyping Consortium Status Dnaaf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031110 VEGA Gene Model | MGI Sequence Detail 23220 C57BL/6J ±  kb
transcript OTTMUST00000077071 VEGA | MGI Sequence Detail 2821 Not Applicable 
polypeptide OTTMUSP00000040662 VEGA | MGI Sequence Detail 634 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001611 Leucine-rich repeat
Protein Ontology PR:000009938 leucine-rich repeat-containing protein 50
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208266 Dong F, et al., Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014 Jan 20;204(2):203-13
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory