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H2al2a Gene Detail
Summary
  • Symbol
    H2al2a
  • Name
    H2A histone family member L2A
  • Synonyms
    1700113O17Rik, H2afb1, H2AL2, Tseg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915481
    NCBI Gene: 68231
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:17996417-17996958 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 12.81 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915481
protein coding gene Chr2:17996417-17996958 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025370
protein coding gene Chr2:15663652-15664193 (-)
A/J MGP_AJ_G0025348
protein coding gene Chr2:15034047-15034588 (-)
AKR/J MGP_AKRJ_G0025316
protein coding gene Chr2:15536252-15536793 (-)
BALB/cJ MGP_BALBcJ_G0025343
protein coding gene Chr2:15066199-15066740 (-)
C3H/HeJ MGP_C3HHeJ_G0025103
protein coding gene Chr2:15438546-15439087 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025785
protein coding gene Chr2:16037935-16038476 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023201
protein coding gene Chr2:14471559-14472025 (-)
CAST/EiJ MGP_CASTEiJ_G0024566
protein coding gene Chr2:15403795-15404257 (-)
CBA/J MGP_CBAJ_G0025082
protein coding gene Chr2:16773062-16773603 (-)
DBA/2J MGP_DBA2J_G0025214
protein coding gene Chr2:14966675-14967216 (-)
FVB/NJ MGP_FVBNJ_G0025177
protein coding gene Chr2:14774616-14775157 (-)
LP/J MGP_LPJ_G0025300
protein coding gene Chr2:15536890-15537431 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025208
protein coding gene Chr2:16710861-16711402 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025844
protein coding gene Chr2:15472010-15472551 (-)
PWK/PhJ MGP_PWKPhJ_G0034429
protein coding gene ChrX:45928394-45928868 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034077
protein coding gene ChrX:4349985-4350449 (-)
WSB/EiJ MGP_WSBEiJ_G0024636
protein coding gene Chr2:15567996-15568458 (-)



Homology
more
  • Human Ortholog
    LOC101928761, dr1-associated corepressor homolog
  • Vertebrate Orthologs
    23
  • Human Ortholog
    LOC101928761, dr1-associated corepressor homolog
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 101928761

  • Chr Location
    X

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68231 NCBI Gene Model | MGI Sequence Detail 542 C57BL/6J ±  kb
transcript NM_026627 RefSeq | MGI Sequence Detail 542 C57BL/6  
polypeptide Q9CQ70 UniProt | EBI | MGI Sequence Detail 111 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:241000 Barral S, et al., Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells. Mol Cell. 2017 Apr 06;66(1):89-101.e8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory