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Tmbim4 Gene Detail
Summary
  • Symbol
    Tmbim4
  • Name
    transmembrane BAX inhibitor motif containing 4
  • Synonyms
    0610007H07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915462
    NCBI Gene: 68212
  • Gene Overview
    MyGene.info: TMBIM4
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:120208826-120224897 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 67.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915462
protein coding gene Chr10:120201590-120224917 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017773
protein coding gene Chr10:123345486-123375081 (+)
A/J MGP_AJ_G0017748
protein coding gene Chr10:118466481-118489986 (+)
AKR/J MGP_AKRJ_G0017711
protein coding gene Chr10:121999727-122024692 (+)
BALB/cJ MGP_BALBcJ_G0017712
protein coding gene Chr10:118854771-118878007 (+)
C3H/HeJ MGP_C3HHeJ_G0017536
protein coding gene Chr10:122204770-122228671 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018167
protein coding gene Chr10:127525406-127552020 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015848
protein coding gene Chr10:112823759-112849928 (+)
CAST/EiJ MGP_CASTEiJ_G0017097
protein coding gene Chr10:122511913-122545515 (+)
CBA/J MGP_CBAJ_G0017505
protein coding gene Chr10:132722009-132751256 (+)
DBA/2J MGP_DBA2J_G0017611
protein coding gene Chr10:117601685-117626997 (+)
FVB/NJ MGP_FVBNJ_G0017606
protein coding gene Chr10:116592631-116618088 (+)
LP/J MGP_LPJ_G0017685
protein coding gene Chr10:123897333-123924709 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017635
protein coding gene Chr10:135337716-135365278 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018208
protein coding gene Chr10:122006531-122034774 (+)
PWK/PhJ MGP_PWKPhJ_G0016881
protein coding gene Chr10:117699309-117724038 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016672
protein coding gene Chr10:120895751-120923072 (+)
WSB/EiJ MGP_WSBEiJ_G0017157
protein coding gene Chr10:122249795-122274448 (+)



Homology
more
  • Human Ortholog
    TMBIM4, transmembrane BAX inhibitor motif containing 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMBIM4, transmembrane BAX inhibitor motif containing 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-119, GAAP, LFG4, S1R, ZPRO
  • Links
    NCBI Gene ID: 51643
    neXtProt AC: NX_Q9HC24
    UniProt: Q9HC24

  • Chr Location
    12q14.3; chr12:66136936-66170072 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    4
  • Genomic Mutations
    1 involving Tmbim4
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68212 NCBI Gene Model | MGI Sequence Detail 16072 C57BL/6J ±  kb
transcript NM_026617 RefSeq | MGI Sequence Detail 808 C57BL/6  
polypeptide Q9DA39 UniProt | EBI | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 95
    cDNA 95

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143748
References
more
  • Summaries
    All 36
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory