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Diras2
Gene Detail
Symbol

Name
ID
Diras2
DIRAS family, GTP-binding RAS-like 2
MGI:1915453
Synonyms
2900052J15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 13
27.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:52504375-52530836 bp, - strand
From Ensembl annotation of GRCm38

  26462 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56777  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DIRAS2
Protein SuperFamily: ras protein
Gene Tree: Diras2

Human
homologs
DIRAS2, DIRAS family, GTP-binding RAS-like 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 54769
neXtProt AC: NX_Q96HU8

Human Synonyms: Di-Ras2

Human Chr (Location): 9q22.2; chr9:90609832-90643105 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Diras2 interacts with 300 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process signal transduction, small GTPase mediated signal transduction
Component membrane, plasma membrane
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (16)    Tissues (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 15
RT-PCR 1
cDNA source data(56)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase diras2    NEW 
Molecular
reagents
All nucleic(59) cDNA(58) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000047842 (Evidence)
Entrez Gene 68203 (Evidence)
UniGene 29362
DFCI TC1630281
DoTS DT.483514
NIA Mouse Gene Index U034779
Consensus CDS Project CCDS26516.1
International Mouse Phenotyping Consortium Status Diras2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047842 Ensembl Gene Model | MGI Sequence Detail 26462 C57BL/6J ±  kb
transcript ENSMUST00000057442 Ensembl | MGI Sequence Detail 4348 Not Applicable 
polypeptide ENSMUSP00000055416 Ensembl | MGI Sequence Detail 199 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(92 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000006487 GTP-binding protein Di-Ras2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204470 Inagawa M, et al., Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis. Mech Dev. 2013 Nov-Dec;130(11-12):519-31
All references(31)
Other
accession IDs
MGI:2145227

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory