About   Help   FAQ
Ndufa5 Gene Detail
Summary
  • Symbol
    Ndufa5
  • Name
    NADH:ubiquinone oxidoreductase subunit A5
  • Synonyms
    2900002J19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915452
    NCBI Gene: 68202
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:24518661-24527689 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 11.28 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915452
protein coding gene Chr6:24518661-24528012 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030494
protein coding gene Chr6:22084190-22094583 (-)
A/J MGP_AJ_G0030467
protein coding gene Chr6:21160964-21170313 (-)
AKR/J MGP_AKRJ_G0030394
protein coding gene Chr6:21835293-21844642 (-)
BALB/cJ MGP_BALBcJ_G0030477
protein coding gene Chr6:21265333-21274682 (-)
C3H/HeJ MGP_C3HHeJ_G0030190
protein coding gene Chr6:21832331-21841678 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030931
protein coding gene Chr6:22780931-22791787 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028142
protein coding gene Chr6:19620564-19629891 (-)
CAST/EiJ MGP_CASTEiJ_G0029592
protein coding gene Chr6:21690948-21700396 (-)
CBA/J MGP_CBAJ_G0030168
protein coding gene Chr6:23542513-23553551 (-)
DBA/2J MGP_DBA2J_G0030312
protein coding gene Chr6:21116011-21125358 (-)
FVB/NJ MGP_FVBNJ_G0030266
protein coding gene Chr6:20880678-20890025 (-)
LP/J MGP_LPJ_G0030399
protein coding gene Chr6:22243889-22253236 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030302
protein coding gene Chr6:25466892-25476865 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030961
protein coding gene Chr6:21769393-21778742 (-)
PWK/PhJ MGP_PWKPhJ_G0029306
protein coding gene Chr6:20675695-20685253 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029142
protein coding gene Chr6:21484684-21494043 (-)
WSB/EiJ MGP_WSBEiJ_G0029668
protein coding gene Chr6:21727769-21737114 (-)



Homology
more
  • Human Ortholog
    NDUFA5, NADH:ubiquinone oxidoreductase subunit A5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFA5, NADH:ubiquinone oxidoreductase subunit A5
  • Synonyms
    B13, CI-13kB, CI-13KD-B, NUFM, UQOR13
  • Links
    NCBI Gene ID: 4698
    neXtProt AC: NX_Q16718
    UniProt: Q16718

  • Chr Location
    7q31.32; chr7:123536997-123601651 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit embryonic lethality at E9.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68202 NCBI Gene Model | MGI Sequence Detail 9029 C57BL/6J ±  kb
transcript NM_026614 RefSeq | MGI Sequence Detail 578 C57BL/6  
polypeptide Q9CPP6 UniProt | EBI | MGI Sequence Detail 116 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 132
    cDNA 131
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:320063 Signes A, et al., Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes. Essays Biochem. 2018 Jul 20;62(3):255-270

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory