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Cgnl1 Gene Detail
Summary
  • Symbol
    Cgnl1
  • Name
    cingulin-like 1
  • Synonyms
    4933421H10Rik, 9930020M10Rik, Jacop
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915428
    NCBI Gene: 68178
  • Gene Overview
    MyGene.info: CGNL1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:71626509-71771602 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 39.85 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1092 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915428
protein coding gene Chr9:71626507-71809300 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035011
protein coding gene Chr9:71748775-71904883 (-)
A/J MGP_AJ_G0034992
protein coding gene Chr9:69239045-69389433 (-)
AKR/J MGP_AKRJ_G0034921
protein coding gene Chr9:70899143-71049567 (-)
BALB/cJ MGP_BALBcJ_G0034984
protein coding gene Chr9:68957059-69107969 (-)
C3H/HeJ MGP_C3HHeJ_G0034693
protein coding gene Chr9:71408945-71561165 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035503
protein coding gene Chr9:73653851-73805449 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032414
protein coding gene Chr9:68757600-68914134 (-)
CAST/EiJ MGP_CASTEiJ_G0034015
protein coding gene Chr9:71693424-71846920 (-)
CBA/J MGP_CBAJ_G0034666
protein coding gene Chr9:76193936-76353882 (-)
DBA/2J MGP_DBA2J_G0034825
protein coding gene Chr9:68972310-69121336 (-)
FVB/NJ MGP_FVBNJ_G0034767
protein coding gene Chr9:68290601-68438471 (-)
LP/J MGP_LPJ_G0034906
protein coding gene Chr9:71962966-72119323 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034808
protein coding gene Chr9:77256969-77408320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035525
protein coding gene Chr9:71043946-71194549 (-)
PWK/PhJ MGP_PWKPhJ_G0033719
protein coding gene Chr9:69224990-69373481 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033552
protein coding gene Chr9:71356133-71509566 (-)
WSB/EiJ MGP_WSBEiJ_G0034127
protein coding gene Chr9:70972245-71120563 (-)



Homology
more
  • Human Ortholog
    CGNL1, cingulin like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CGNL1, cingulin like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    JACOP, PCING
  • Links
    NCBI Gene ID: 84952
    neXtProt AC: NX_Q0VF96
    UniProt: Q0VF96

  • Chr Location
    15q21.3; chr15:57376487-57550727 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41901
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CGNL1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032232 Ensembl Gene Model | MGI Sequence Detail 145094 C57BL/6J ±  kb
transcript ENSMUST00000122065 Ensembl | MGI Sequence Detail 4487 Not Applicable  
polypeptide ENSMUSP00000112479 Ensembl | MGI Sequence Detail 1297 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR002928 Myosin tail
Molecular
Reagents
less
  • All nucleic 80
    cDNA 79
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:2143083, MGI:2443993
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:258537 Chrifi I, et al., Cgnl1, an endothelial junction complex protein, regulates GTPase mediated angiogenesis. Cardiovasc Res. 2017 Dec 1;113(14):1776-1788

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory