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Gtf2e2
Gene Detail
Symbol

Name
ID
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
MGI:1915403
Synonyms
34kDa, C330006J08Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 8
20.79 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:33731833-33777164 bp, + strand
From VEGA annotation of GRCm38

  45332 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37573  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GTF2E2
Protein SuperFamily: transcription initiation factor IIE, beta subunit
Gene Tree: Gtf2e2

Human
homologs
GTF2E2, general transcription factor IIE, polypeptide 2, beta 34kDa
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 2961
neXtProt AC: NX_P29084

Human Synonyms: FE, TF2E2, TFIIE-B

Human Chr (Location): 8p12; chr8:30578514-30658241 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(49) : Gene trapped(47) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gtf2e2 interacts with 105 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated, ...
Component cytoplasm, nucleoplasm, ...
Function DNA binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (62)    Tissues (9)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 62
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA GTF2E2 ; Xenbase gtf2e2    NEW 
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000049715 (Evidence)
Ensembl Gene Model ENSMUSG00000031585 (Evidence)
Entrez Gene 68153 (Evidence)
DFCI TC1642918, TC1574849
DoTS DT.50316942, DT.94372681, DT.97376901
NIA Mouse Gene Index U009246
Consensus CDS Project CCDS22236.1
International Mouse Phenotyping Consortium Status Gtf2e2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049715 VEGA Gene Model | MGI Sequence Detail 45332 C57BL/6J ±  kb
transcript OTTMUST00000126634 VEGA | MGI Sequence Detail 1634 Not Applicable 
polypeptide OTTMUSP00000068452 VEGA | MGI Sequence Detail 292 Not Applicable 

For the selected sequences
All sequences(72) RefSeq(14) UniProt(6)
Polymorphisms
SNPs within 2kb(215 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003166 Transcription factor TFIIE beta subunit, DNA-binding domain
InterPro IPR016656 Transcription initiation factor TFIIE, beta subunit
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000029777 transcription initiation factor IIE subunit beta
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000
All references(40)
Other
accession IDs
MGI:2142560

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory