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Gtf2e2 Gene Detail
Summary
  • Symbol
    Gtf2e2
  • Name
    general transcription factor II E, polypeptide 2 (beta subunit)
  • Synonyms
    34kDa, C330006J08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915403
    NCBI Gene: 68153
  • Gene Overview
    MyGene.info: GTF2E2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:33731914-33777173 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 20.79 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    211 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915403
protein coding gene Chr8:33731833-33777173 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033527
protein coding gene Chr8:32190097-32243566 (+)
A/J MGP_AJ_G0033507
protein coding gene Chr8:30961293-31006735 (+)
AKR/J MGP_AKRJ_G0033431
protein coding gene Chr8:31927996-31977502 (+)
BALB/cJ MGP_BALBcJ_G0033503
protein coding gene Chr8:31082655-31127940 (+)
C3H/HeJ MGP_C3HHeJ_G0033215
protein coding gene Chr8:32252517-32300409 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034019
protein coding gene Chr8:33431017-33479182 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030968
protein coding gene Chr8:27964354-28011220 (+)
CAST/EiJ MGP_CASTEiJ_G0032542
protein coding gene Chr8:31693013-31742402 (+)
CBA/J MGP_CBAJ_G0033193
protein coding gene Chr8:34736845-34792298 (+)
DBA/2J MGP_DBA2J_G0033346
protein coding gene Chr8:30939639-30984712 (+)
FVB/NJ MGP_FVBNJ_G0033291
protein coding gene Chr8:30603310-30648715 (+)
LP/J MGP_LPJ_G0033436
protein coding gene Chr8:32156354-32207322 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033333
protein coding gene Chr8:34271408-34321858 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034038
protein coding gene Chr8:32018400-32066392 (+)
PWK/PhJ MGP_PWKPhJ_G0032254
protein coding gene Chr8:30456049-30501622 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032085
protein coding gene Chr8:31283857-31331531 (+)
WSB/EiJ MGP_WSBEiJ_G0032658
protein coding gene Chr8:32150401-32201370 (+)



Homology
more
  • Human Ortholog
    GTF2E2, general transcription factor IIE subunit 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GTF2E2, general transcription factor IIE subunit 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FE, TF2E2, TFIIE-B, TTD6
  • Links
    NCBI Gene ID: 2961
    neXtProt AC: NX_P29084
    UniProt: P29084

  • Chr Location
    8p12; chr8:30578514-30658241 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68153 NCBI Gene Model | MGI Sequence Detail 45260 C57BL/6J ±  kb
transcript NM_001167922 RefSeq | MGI Sequence Detail 1664 C57BL/6  
polypeptide Q9D902 UniProt | EBI | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000029777 transcription initiation factor IIE subunit beta
  • InterPro Domains
    IPR003166 Transcription factor TFIIE beta subunit, DNA-binding domain
    IPR016656 Transcription initiation factor TFIIE, beta subunit
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
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  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142560
References
more
  • Summaries
    All 44
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:61657 De Graeve F, et al., A murine ATFa-associated factor with transcriptional repressing activity. Oncogene. 2000 Mar 30;19(14):1807-19
  • Latest
    J:228779 Alpern D, et al., TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. Elife. 2014;3:e03613

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory