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Otub2 Gene Detail
Summary
  • Symbol
    Otub2
  • Name
    OTU domain, ubiquitin aldehyde binding 2
  • Synonyms
    2010015L18Rik, 4930586I02Rik, OTB2, OTU2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915399
    NCBI Gene: 68149
  • Gene Overview
    MyGene.info: OTUB2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:103388682-103406350 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 52.92 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    193 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915399
protein coding gene Chr12:103376894-103406350 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020047
protein coding gene Chr12:105068072-105085563 (+)
A/J MGP_AJ_G0020003
protein coding gene Chr12:101029350-101047004 (+)
AKR/J MGP_AKRJ_G0019979
protein coding gene Chr12:103878792-103896457 (+)
BALB/cJ MGP_BALBcJ_G0019989
protein coding gene Chr12:101385280-101402945 (+)
C3H/HeJ MGP_C3HHeJ_G0019791
protein coding gene Chr12:104371519-104389074 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020438
protein coding gene Chr12:108332349-108351490 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018051
protein coding gene Chr12:98070790-98088388 (+)
CAST/EiJ MGP_CASTEiJ_G0019337
protein coding gene Chr12:99222746-99242662 (+)
CBA/J MGP_CBAJ_G0019763
protein coding gene Chr12:112358991-112378932 (+)
DBA/2J MGP_DBA2J_G0019874
protein coding gene Chr12:100551111-100568928 (+)
FVB/NJ MGP_FVBNJ_G0019863
protein coding gene Chr12:99285043-99302711 (+)
LP/J MGP_LPJ_G0019950
protein coding gene Chr12:104915316-104932773 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019903
protein coding gene Chr12:115814428-115834307 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020467
protein coding gene Chr12:103414959-103433468 (+)
PWK/PhJ MGP_PWKPhJ_G0019100
protein coding gene Chr12:95112353-95130739 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018896
protein coding gene Chr12:97616249-97635554 (+)
WSB/EiJ MGP_WSBEiJ_G0019391
protein coding gene Chr12:104301923-104319315 (+)



Homology
more
  • Human Ortholog
    OTUB2, OTU deubiquitinase, ubiquitin aldehyde binding 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    OTUB2, OTU deubiquitinase, ubiquitin aldehyde binding 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf137, OTB2, OTU2
  • Links
    NCBI Gene ID: 78990
    neXtProt AC: NX_Q96DC9
    UniProt: Q96DC9

  • Chr Location
    14q32.12; chr14:94016083-94048933 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Otub2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021203 Ensembl Gene Model | MGI Sequence Detail 17669 C57BL/6J ±  kb
transcript ENSMUST00000179684 Ensembl | MGI Sequence Detail 2890 Not Applicable  
polypeptide ENSMUSP00000137162 Ensembl | MGI Sequence Detail 323 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919646, MGI:2144803, MGI:2145047
References
more
  • Summaries
    All 29
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory