Arl13b
Gene Detail

Symbol Name ID

Arl13b ADP-ribosylation factor-like 13B MGI:1915396

Synonyms

A530097K21Rik, A930014M17Rik, Arl2l1, C530009C10Rik, hnn

Feature Type

protein coding gene

Genetic Map

Chromosome 16

36.43 cM, cytoband C1.2
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr16:62793685-62847040 bp, - strand From VEGA annotation of GRCm38   53356 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:18820  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ADP-ribosylation factor
Gene Tree: Arl13b

Human homologs

Human Homolog		ARL13B, ADP-ribosylation factor-like 13B
NCBI Gene ID		200894
neXtProt AC		NX_Q3SXY8
Human Synonyms		ARL2L1, JBTS8
Human Chr (Location)		3q11.1; chr3:93698983-93774522 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ARL13B

Alleles and phenotypes

All alleles(8) : Targeted(4) Gene trapped(3) Chemically induced(1)
 

Mice homozygous for an ENU-induced mutation die at E13-E14 exhibiting left-right randomization and absence of the floor plate in the caudal spinal cord.

 

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	determination of left/right symmetry, dorsal/ventral pattern formation, ...
Component	cilium, intracellular
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (30 records)
Data Summary: Results (6)    Tissues (3)    Images (6)
Theiler Stages: 19

Assay Type	Results
Immunohistochemistry	6

cDNA source data(44)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(44) cDNA(44)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000024090 (Evidence)
Ensembl Gene Model	ENSMUSG00000022911 (Evidence)
Entrez Gene	68146 (Evidence)
UniGene	96833
DFCI	TC1579368, TC1596969, TC1617432, TC1622845
DoTS	DT.101725269, DT.91368919, DT.97342607, DT.97359833, DT.97390667
NIA Mouse Gene Index	U037170
Consensus CDS Project	CCDS28261.1
International Mouse Knockout Project Status	Arl13b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024090	VEGA Gene Model | MGI Sequence Detail	53356	C57BL/6J
transcript	OTTMUST00000058920	VEGA | MGI Sequence Detail	3528	Not Applicable
polypeptide	OTTMUSP00000028614	VEGA | MGI Sequence Detail	427	Not Applicable

All sequences(37) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(274 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006689	Small GTPase superfamily, ARF/SAR type
InterPro	IPR024156	Small GTPase superfamily, ARF type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000004277	ADP-ribosylation factor-like protein 13B

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193186 Barral DC, et al., Arl13b regulates endocytic recycling traffic. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21354-9
All references(71)

Other accession IDs

MGI:1925200, MGI:3026930, MGI:3578137