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Arl13b
Gene Detail
 Symbol
Name
ID
Arl13b
ADP-ribosylation factor-like 13B
MGI:1915396
Synonyms A530097K21Rik, A930014M17Rik, Arl2l1, C530009C10Rik, hnn
Feature Type protein coding gene
Genetic Map
Chromosome 16
36.43 cM, cytoband C1.2
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr16:62793685-62847040 bp, - strand
From VEGA annotation of GRCm38

  53356 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18820  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ADP-ribosylation factor
Gene Tree: Arl13b

Human
homologs
Human Homolog ARL13B, ADP-ribosylation factor-like 13B
NCBI Gene ID 200894
neXtProt AC  NX_Q3SXY8
Human Synonyms  ARL2L1, JBTS8
Human Chr (Location)  3q11.1; chr3:93980139-94055678 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ARL13B
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Chemically induced (ENU)(1) Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced mutation die at E13-E14 exhibiting left-right randomization and absence of the floor plate in the caudal spinal cord.
 
Interactions
Arl13b interacts with 292 markers (Mir7-1, Mir15b, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cilium assembly, determination of left/right symmetry, ...
Component cell projection, ciliary membrane, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (37 records)
Data Summary: Results (6)    Tissues (3)    Images (6)
Theiler Stages: 19
Assay TypeResults
Immunohistochemistry 6
cDNA source data(41)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(41) cDNA(41)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000024090 (Evidence)
Ensembl Gene ModelENSMUSG00000022911 (Evidence)
Entrez Gene68146 (Evidence)
UniGene96833
DFCITC1579368, TC1596969, TC1617432, TC1622845
DoTSDT.101725269, DT.91368919, DT.97342607, DT.97359833, DT.97390667
NIA Mouse Gene IndexU037170
Consensus CDS ProjectCCDS28261.1
International Mouse Knockout Project StatusArl13b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024090 VEGA Gene Model | MGI Sequence Detail 53356 C57BL/6J ±  kb
transcript OTTMUST00000058920 VEGA | MGI Sequence Detail 3528 Not Applicable 
polypeptide OTTMUSP00000028614 VEGA | MGI Sequence Detail 427 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(281 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR006689 Small GTPase superfamily, ARF/SAR type
InterPro IPR024156 Small GTPase superfamily, ARF type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000004277 ADP-ribosylation factor-like protein 13B
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208632 Bazzi H, et al., Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1491-500
All references(82)
Other
accession IDs
MGI:1925200, MGI:3026930, MGI:3578137

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory