About   Help   FAQ
Arl13b Gene Detail
Summary
  • Symbol
    Arl13b
  • Name
    ADP-ribosylation factor-like 13B
  • Synonyms
    A530097K21Rik, A930014M17Rik, Arl2l1, C530009C10Rik, hnn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915396
    NCBI Gene: 68146
  • Gene Overview
    MyGene.info: ARL13B
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:62793685-62847040 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 36.43 cM, cytoband C1.2
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    280 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915396
protein coding gene Chr16:62793308-62847053 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022935
protein coding gene Chr16:62189360-62252629 (-)
A/J MGP_AJ_G0022903
protein coding gene Chr16:59559236-59611924 (-)
AKR/J MGP_AKRJ_G0022873
protein coding gene Chr16:61396984-61451469 (-)
BALB/cJ MGP_BALBcJ_G0022905
protein coding gene Chr16:59758779-59816594 (-)
C3H/HeJ MGP_C3HHeJ_G0022667
protein coding gene Chr16:61715441-61767811 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023353
protein coding gene Chr16:64060570-64123334 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020856
protein coding gene Chr16:58722887-58776179 (-)
CAST/EiJ MGP_CASTEiJ_G0022191
protein coding gene Chr16:61935397-61992916 (-)
CBA/J MGP_CBAJ_G0022638
protein coding gene Chr16:66684869-66737549 (-)
DBA/2J MGP_DBA2J_G0022770
protein coding gene Chr16:59326003-59378743 (-)
FVB/NJ MGP_FVBNJ_G0022744
protein coding gene Chr16:58969322-59025381 (-)
LP/J MGP_LPJ_G0022839
protein coding gene Chr16:62046530-62102935 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022763
protein coding gene Chr16:67746982-67805455 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023369
protein coding gene Chr16:61477873-61533034 (-)
PWK/PhJ MGP_PWKPhJ_G0021933
protein coding gene Chr16:59510762-59564510 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021763
protein coding gene Chr16:61232891-61286323 (-)
WSB/EiJ MGP_WSBEiJ_G0022237
protein coding gene Chr16:61565394-61623437 (-)



Homology
more
  • Human Ortholog
    ARL13B, ADP ribosylation factor like GTPase 13B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARL13B, ADP ribosylation factor like GTPase 13B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARL2L1, JBTS8
  • Links
    NCBI Gene ID: 200894
    neXtProt AC: NX_Q3SXY8
    UniProt: Q3SXY8

  • Chr Location
    3q11.1-q11.2; chr3:93980139-94055678 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ARL13B associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotypes from 3 alleles in 5 genetic backgrounds
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation die at E13-E14 exhibiting left-right randomization and absence of the floor plate in the caudal spinal cord.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022911 Ensembl Gene Model | MGI Sequence Detail 53356 C57BL/6J ±  kb
    transcript ENSMUST00000089289 Ensembl | MGI Sequence Detail 3528 Not Applicable  
    polypeptide ENSMUSP00000086703 Ensembl | MGI Sequence Detail 427 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000004277 ADP-ribosylation factor-like protein 13B
    • InterPro Domains
      IPR027417 P-loop containing nucleoside triphosphate hydrolase
      IPR006689 Small GTPase superfamily, ARF/SAR type
      IPR005225 Small GTP-binding protein domain
    Molecular
    Reagents
    less
    • All nucleic 42
      cDNA 42

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1925200, MGI:3026930, MGI:3578137
    References
    more
    • Summaries
      All 145
      Developmental Gene Expression 90
      Gene Ontology 19
      Phenotypes 25
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:263095 Koefoed K, et al., The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development. Sci Rep. 2018 Jun 22;8(1):9542

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory