Herpud2 MGI Mouse Gene Detail - MGI:1915393

Symbol

Herpud2
Name

HERPUD family member 2
Synonyms

5031400M07Rik

Feature Type

protein coding gene
IDs

MGI:1915393
NCBI Gene: 80517
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr9:25019428-25063116 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 10.25 cM, cytoband A4
Mapping Data

2 experiments

SNPs within 2kb

135 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915393	protein coding gene	Chr9:25012412-25063116 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0034496	protein coding gene	Chr9:22517879-22566083 (-)
A/J	MGP_AJ_G0034474	protein coding gene	Chr9:22040881-22084681 (-)
AKR/J	MGP_AKRJ_G0034400	protein coding gene	Chr9:22469953-22510802 (-)
BALB/cJ	MGP_BALBcJ_G0034465	protein coding gene	Chr9:21942634-21986303 (-)
C3H/HeJ	MGP_C3HHeJ_G0034177	protein coding gene	Chr9:22801630-22846062 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0034986	protein coding gene	Chr9:23385021-23431799 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031916	protein coding gene	Chr9:20983374-21035246 (-)
CAST/EiJ	MGP_CASTEiJ_G0033499	protein coding gene	Chr9:22663132-22710791 (-)
CBA/J	MGP_CBAJ_G0034150	protein coding gene	Chr9:24242244-24298550 (-)
DBA/2J	MGP_DBA2J_G0034308	protein coding gene	Chr9:22018331-22064761 (-)
FVB/NJ	MGP_FVBNJ_G0034251	protein coding gene	Chr9:21510657-21559710 (-)
LP/J	MGP_LPJ_G0034394	protein coding gene	Chr9:22699760-22744207 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034294	protein coding gene	Chr9:25866499-25917429 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035006	protein coding gene	Chr9:22454928-22501354 (-)
PWK/PhJ	MGP_PWKPhJ_G0033205	protein coding gene	Chr9:21966741-22010487 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0033039	protein coding gene	Chr9:22496364-22554121 (-)
WSB/EiJ	MGP_WSBEiJ_G0033615	protein coding gene	Chr9:22175964-22224940 (-)

Human Ortholog

HERPUD2, HERPUD family member 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

HERPUD2, HERPUD family member 2
Links

HGNC:21915

NCBI Gene ID: 64224

neXtProt AC: NX_Q9BSE4

UniProt: Q9BSE4
Chr Location

7p14.2; chr7:35632659-35697459 (-) GRCh38

MGI Vertebrate Homology

Herpud2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: HERPUD2
Gene Tree

Herpud2

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

13
Endonuclease-mediated

1
Gene trapped

7
Spontaneous

1
Targeted

4
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

21 strains or lines available

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All GO Annotations

3
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

829
Tissues

46
cDNA Data

47
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase herpud2

ZFIN herpud2

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All Sequences

52
RefSeq

4
UniProt

1
CCDS

CCDS22934.1

Ensembl

ENSMUSG00000008429 (Evidence)
NCBI Gene

80517

			Length	Strain/Species	Flank
genomic	ENSMUSG00000008429	Ensembl Gene Model \| MGI Sequence Detail	43689	C57BL/6J	± kb
transcript	ENSMUST00000008573	Ensembl \| MGI Sequence Detail	2781	Not Applicable
polypeptide	ENSMUSP00000008573	Ensembl \| MGI Sequence Detail	404	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000008514 homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

(term hierarchy)
InterPro Domains

IPR039751 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 /2

IPR000626 Ubiquitin-like domain

IPR029071 Ubiquitin-like domain superfamily

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All nucleic 47

cDNA 47

Microarray probesets 5

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MGI:1930872

Summaries

All 37

Developmental Gene Expression 1

Gene Ontology 3

Phenotypes 12
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:296898 Tonelli Gombalova Z, et al., Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. J Comp Neurol. 2020 Oct 15;528(15):2523-2550

TSS for Herpud2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr88525	Chr9:25063068-25063136 (-)	14 bp
Tssr88524	Chr9:25063011-25063053 (-)	84 bp
Tssr88523	Chr9:25062983-25063000 (-)	124 bp
Tssr88522	Chr9:25062961-25062972 (-)	149 bp
Tssr88521	Chr9:25062941-25062950 (-)	170 bp
Tssr88520	Chr9:25062906-25062922 (-)	202 bp
Tssr88519	Chr9:25062537-25062548 (-)	573 bp
Tssr88518	Chr9:25062501-25062535 (-)	598 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23