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Upf3b
Gene Detail
 Symbol
Name
ID
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
MGI:1915384
Synonyms 5730594O13Rik, RENT3B, UPF3X
Feature Type protein coding gene
Genetic Map
Chromosome X
21.51 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:37091678-37110322 bp, - strand
From VEGA annotation of GRCm38

  18645 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11307  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Upf3b

Human
homologs
Human Homolog UPF3B, UPF3 regulator of nonsense transcripts homolog B (yeast)
NCBI Gene ID 65109
neXtProt AC  NX_Q9BZI7
Human Synonyms  HUPF3B, MRX62, MRXS14, RENT3B, UPF3X
Human Chr (Location)  Xq25-q26; chrX:119807043-119853028 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human UPF3B
Alleles
and
phenotypes
All alleles(14) : Targeted(4) Gene trapped(10)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of translation, ...
Component cytoplasm, exon-exon junction complex, ...
Function mRNA binding, poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(44)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(44) cDNA(44)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000017109 (Evidence)
Ensembl Gene ModelENSMUSG00000036572 (Evidence)
Entrez Gene68134 (Evidence)
UniGene271160
DFCITC1582120, TC1586515, TC1617176, TC1728743
DoTSDT.101149861, DT.101407708, DT.529139, DT.97395054
NIA Mouse Gene IndexU039318
Consensus CDS ProjectCCDS30068.1
International Mouse Knockout Project StatusUpf3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017109 VEGA Gene Model | MGI Sequence Detail 18645 C57BL/6J ±  kb
transcript OTTMUST00000041431 VEGA | MGI Sequence Detail 2344 Not Applicable 
polypeptide OTTMUSP00000018591 VEGA | MGI Sequence Detail 472 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(4) UniProt(5)
Polymorphisms SNPs within 2kb(29 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR005120 Regulator of nonsense-mediated decay, UPF3
Protein Ontology PR:000017111 regulator of nonsense transcripts 3B
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202619 Leoyklang P, et al., Disorders with similar clinical phenotypes reveal underlying genetic interaction: SATB2 acts as an activator of the UPF3B gene. Hum Genet. 2013 Dec;132(12):1383-93
All references(36)
Other
accession IDs
MGI:2147871, MGI:2148018

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory