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Upf3b
Gene Detail
Symbol

Name
ID
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
MGI:1915384
Synonyms
5730594O13Rik, RENT3B, UPF3X
Feature Type
protein coding gene
Genetic Map
Chromosome X
21.51 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:37091678-37110322 bp, - strand
From VEGA annotation of GRCm38

  18645 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11307  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: UPF3B
Gene Tree: Upf3b

Human
homologs
UPF3B, UPF3 regulator of nonsense transcripts homolog B (yeast)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 65109
neXtProt AC: NX_Q9BZI7

Human Synonyms: HUPF3B, MRX62, MRXS14, RENT3B, UPF3X

Human Chr (Location): Xq24; chrX:119805311-119853028 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human UPF3B

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(10) Targeted(4)
Incidental mutations (data from APF )
Interactions
Upf3b interacts with 152 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (73)    Tissues (31)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 37
RNA in situ 27
RT-PCR 9
cDNA source data(44)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase upf3b ; ZFIN upf3b    NEW 
Molecular
reagents
All nucleic(50) cDNA(46) Primer pair(4)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000017109 (Evidence)
Ensembl Gene Model ENSMUSG00000036572 (Evidence)
Entrez Gene 68134 (Evidence)
UniGene 271160
DFCI TC1582120, TC1586515, TC1617176, TC1728743
DoTS DT.101149861, DT.101407708, DT.529139, DT.97395054
NIA Mouse Gene Index U039318
Consensus CDS Project CCDS30068.1
International Mouse Phenotyping Consortium Status Upf3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017109 VEGA Gene Model | MGI Sequence Detail 18645 C57BL/6J ±  kb
transcript OTTMUST00000041431 VEGA | MGI Sequence Detail 2344 Not Applicable 
polypeptide OTTMUSP00000018591 VEGA | MGI Sequence Detail 472 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(29 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding alpha-beta plait domain
InterPro IPR005120 Regulator of nonsense-mediated decay, UPF3
Protein Ontology PR:000017111 regulator of nonsense transcripts 3B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:222866 Karam R, et al., The unfolded protein response is shaped by the NMD pathway. EMBO Rep. 2015 May;16(5):599-609
All references(36)
Other
accession IDs
MGI:2147871, MGI:2148018

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory