About   Help   FAQ
Nkain4 Gene Detail
Summary
  • Symbol
    Nkain4
  • Name
    Na+/K+ transporting ATPase interacting 4
  • Synonyms
    C030019F02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915372
    NCBI Gene: 58237
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:180934772-180954699 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 103.53 cM, cytoband H4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    183 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915372
protein coding gene Chr2:180934766-180954891 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027006
protein coding gene Chr2:187501873-187521880 (-)
A/J MGP_AJ_G0026972
protein coding gene Chr2:179787680-179807706 (-)
AKR/J MGP_AKRJ_G0026942
protein coding gene Chr2:185178019-185198072 (-)
BALB/cJ MGP_BALBcJ_G0026981
protein coding gene Chr2:180248602-180269311 (-)
C3H/HeJ MGP_C3HHeJ_G0026722
protein coding gene Chr2:185536361-185556346 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027427
protein coding gene Chr2:192926034-192947159 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024792
protein coding gene Chr2:170474628-170493704 (-)
CAST/EiJ MGP_CASTEiJ_G0026181
protein coding gene Chr2:183782840-183803750 (-)
CBA/J MGP_CBAJ_G0026699
protein coding gene Chr2:199911784-199935131 (-)
DBA/2J MGP_DBA2J_G0026837
protein coding gene Chr2:178880633-178900790 (-)
FVB/NJ MGP_FVBNJ_G0026803
protein coding gene Chr2:177493795-177514264 (-)
LP/J MGP_LPJ_G0026938
protein coding gene Chr2:187509754-187535876 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026822
protein coding gene Chr2:202494636-202515718 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027486
protein coding gene Chr2:185146235-185169252 (-)
PWK/PhJ MGP_PWKPhJ_G0025917
protein coding gene Chr2:176406187-176426210 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025717
protein coding gene Chr2:181635911-181656925 (-)
WSB/EiJ MGP_WSBEiJ_G0026253
protein coding gene Chr2:186132377-186153044 (-)



Homology
more
  • Human Ortholog
    NKAIN4, sodium/potassium transporting ATPase interacting 4
  • Vertebrate Orthologs
    8
  • Human Ortholog
    NKAIN4, sodium/potassium transporting ATPase interacting 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA261N11.2, C20orf58, FAM77A
  • Links
    NCBI Gene ID: 128414
    neXtProt AC: NX_Q8IVV8
    UniProt: Q8IVV8

  • Chr Location
    20q13.33; chr20:63240784-63254904 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027574 Ensembl Gene Model | MGI Sequence Detail 19928 C57BL/6J ±  kb
transcript ENSMUST00000103053 Ensembl | MGI Sequence Detail 950 Not Applicable  
polypeptide ENSMUSP00000099342 Ensembl | MGI Sequence Detail 208 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000011229 sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4
  • InterPro Domains
    IPR008516 Na,K-Atpase Interacting protein
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1927556
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:64911 Inoue S, et al., Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Biochem Biophys Res Commun. 2000 Feb 16;268(2):553-61
  • Latest
    J:259186 Heng X, et al., Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory