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Sh3bgrl2 Gene Detail
Summary
  • Symbol
    Sh3bgrl2
  • Name
    SH3 domain binding glutamic acid-rich protein like 2
  • Synonyms
    A930014C21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915350
    NCBI Gene: 212531
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:83430391-83482345 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 45.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1857 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915350
 protein coding gene Chr9:83430380-83520854 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035087
 protein coding gene Chr9:84224861-84316757 (+)
A/J MGP_AJ_G0035068
 protein coding gene Chr9:81307077-81399468 (+)
AKR/J MGP_AKRJ_G0034996
 protein coding gene Chr9:83201273-83305631 (+)
BALB/cJ MGP_BALBcJ_G0035056
 protein coding gene Chr9:80954565-81046220 (+)
C3H/HeJ MGP_C3HHeJ_G0034768
 protein coding gene Chr9:83731829-83825152 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035579
 protein coding gene Chr9:86533878-86628053 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032487
 protein coding gene Chr9:80223213-80313208 (+)
CAST/EiJ MGP_CASTEiJ_G0034086
 protein coding gene Chr9:84126230-84231890 (+)
CBA/J MGP_CBAJ_G0034741
 protein coding gene Chr9:89619318-89721746 (+)
DBA/2J MGP_DBA2J_G0034899
 protein coding gene Chr9:80898096-80989568 (+)
FVB/NJ MGP_FVBNJ_G0034842
 protein coding gene Chr9:80030135-80120547 (+)
LP/J MGP_LPJ_G0034980
 protein coding gene Chr9:84426850-84523551 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034884
 protein coding gene Chr9:91026694-91125009 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035600
 protein coding gene Chr9:83385492-83481253 (+)
PWK/PhJ MGP_PWKPhJ_G0033790
 protein coding gene Chr9:81049019-81143203 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033626
 protein coding gene Chr9:83535804-83625746 (+)
WSB/EiJ MGP_WSBEiJ_G0034203
 protein coding gene Chr9:83363389-83467124 (+)



Homology
more
  • Human Ortholog
    SH3BGRL2, SH3 domain binding glutamate rich protein like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SH3BGRL2, SH3 domain binding glutamate rich protein like 2
  • Links
    NCBI Gene ID: 83699
    UniProt: Q9UJC5

  • Chr Location
    6q14.1; chr6:79537185-79703655 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    5
  • cDNA Data
    66
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 212531 NCBI Gene Model | MGI Sequence Detail 51955 C57BL/6J ±  kb
transcript NM_172507 RefSeq | MGI Sequence Detail 3501 C57BL/6  
polypeptide Q8BG73 UniProt | EBI | MGI Sequence Detail 107 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000030773 SH3 domain-binding glutamic acid-rich-like protein 2
    (term hierarchy)
  • InterPro Domains
    IPR006993 SH3-binding, glutamic acid-rich protein
    IPR051033 SH3 domain-binding glutamic acid-rich protein
    IPR036249 Thioredoxin-like superfamily
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142916
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory