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Rchy1
Gene Detail
Symbol

Name
ID
Rchy1
ring finger and CHY zinc finger domain containing 1
MGI:1915348
Synonyms
6720407C15Rik, Pirh2, PRO1996, Zfp363
Feature Type
protein coding gene
Genetic Map
Chromosome 5
45.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:91948904-91963068 bp, - strand
From VEGA annotation of GRCm38

  14165 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22894  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RCHY1
Gene Tree: Rchy1

Human
homologs
RCHY1, ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 25898
neXtProt AC: NX_Q96PM5

Human Synonyms: ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363

Human Chr (Location): 4q21.1; chr4:75479037-75514744 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mouse embryonic fibroblasts from mice homozygous for a knock-out allele exhibit decreased cellular sensitivity to UV irradiation.
 
Interactions
Rchy1 interacts with 104 markers (Mir10a, Mir10b, Mir16-1, ...)
Expression
Literature Summary: (2 records)
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rchy1 ; ZFIN rchy1    NEW 
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000020371 (Evidence)
Ensembl Gene Model ENSMUSG00000029397 (Evidence)
Entrez Gene 68098 (Evidence)
DFCI TC1600271, TC1575916, TC1695402
NIA Mouse Gene Index U026398
EC 6.3.2.-
PDB 2ECM, 2DKT
Consensus CDS Project CCDS19424.1, CCDS71613.1
International Mouse Phenotyping Consortium Status Rchy1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020371 VEGA Gene Model | MGI Sequence Detail 14165 C57BL/6J ±  kb
transcript OTTMUST00000048310 VEGA | MGI Sequence Detail 1967 Not Applicable 
polypeptide OTTMUSP00000022111 VEGA | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(7) UniProt(3)
Polymorphisms
SNPs within 2kb(117 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004039 Rubredoxin-type fold
InterPro IPR008913 Zinc finger, CHY-type
InterPro IPR017921 Zinc finger, CTCHY-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000029894 RING finger and CHY zinc finger domain-containing protein 1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:197270 Jung YS, et al., Pirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63. J Invest Dermatol. 2013 May;133(5):1178-87
All references(35)
Other
accession IDs
MGI:2141088

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory