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Rchy1
Gene Detail
 Symbol
Name
ID
Rchy1
ring finger and CHY zinc finger domain containing 1
MGI:1915348
Synonyms 6720407C15Rik, Pirh2, PRO1996, Zfp363
Feature Type protein coding gene
Genetic Map
Chromosome 5
45.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:91948904-91963068 bp, - strand
From VEGA annotation of GRCm38

  14165 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22894  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Rchy1

Human
homologs
Human Homolog RCHY1, ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
NCBI Gene ID 25898
neXtProt AC  NX_Q96PM5
Human Synonyms  ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
Human Chr (Location)  4q21.1; chr4:75479037-75514674 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mouse embryonic fibroblasts from mice homozygous for a knock-out allele exhibit decreased cellular sensitivity to UV irradiation.
 
Interactions
Rchy1 interacts with 104 markers (Mir10a, Mir10b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, ...
Component cytoplasm, nucleus, ...
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000020371 (Evidence)
Ensembl Gene ModelENSMUSG00000029397 (Evidence)
Entrez Gene68098 (Evidence)
DFCITC1575916, TC1600271, TC1695402
NIA Mouse Gene IndexU026398
EC6.3.2.-
PDB2DKT, 2ECM
Consensus CDS ProjectCCDS19424.1, CCDS71613.1
International Mouse Knockout Project StatusRchy1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020371 VEGA Gene Model | MGI Sequence Detail 14165 C57BL/6J ±  kb
transcript OTTMUST00000048310 VEGA | MGI Sequence Detail 1967 Not Applicable 
polypeptide OTTMUSP00000022111 VEGA | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(7) UniProt(3)
Polymorphisms SNPs within 2kb(117 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004039 Rubredoxin-type fold
InterPro IPR008913 Zinc finger, CHY-type
InterPro IPR017921 Zinc finger, CTCHY-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000029894 RING finger and CHY zinc finger domain-containing protein 1
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:197270 Jung YS, et al., Pirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63. J Invest Dermatol. 2013 May;133(5):1178-87
All references(37)
Other
accession IDs
MGI:2141088

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory