About   Help   FAQ
Atp5s Gene Detail
Summary
  • Symbol
    Atp5s
  • Name
    ATP synthase, H+ transporting, mitochondrial F0 complex, subunit S
  • Synonyms
    1110015E18Rik, facyor B
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915305
    NCBI Gene: 68055
  • Gene Overview
    MyGene.info: ATP5S
Location & Maps
more
  • Sequence Map
    Chr12:69724962-69744658 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19697 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 28.94 cM, cytoband C3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ATP5S, ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ATP5S, ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ATPW, FB, HSU79253
  • Links
    NCBI Gene ID: 27109
    neXtProt AC: NX_Q99766

  • Chr Location
    14q21.3; chr14:50312329-50326715 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    20
  • Chemically induced (other)
    1
  • Gene trapped
    16
  • Targeted
    3
  • Genomic Mutations
    1 involving Atp5s
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054894 Ensembl Gene Model | MGI Sequence Detail 19697 C57BL/6J ±  kb
transcript ENSMUST00000021372 Ensembl | MGI Sequence Detail 1485 Not Applicable  
polypeptide ENSMUSP00000021372 Ensembl | MGI Sequence Detail 200 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    79 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004466 ATP synthase subunit s, mitochondrial
  • InterPro Domains
    IPR026063 ATP synthase subunit s, mitochondrial
    IPR032675 Leucine-rich repeat domain, L domain-like
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:113816 Sanadi DR, et al., Evidence for the involvement of coupling factor B in the H+ channel of the mitochondrial H+-ATPase. Proc Natl Acad Sci U S A. 1984 Mar;81(5):1371-4
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory