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Atp5s Gene Detail
Summary
  • Symbol
    Atp5s
  • Name
    ATP synthase, H+ transporting, mitochondrial F0 complex, subunit S
  • Synonyms
    1110015E18Rik, facyor B
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915305
    NCBI Gene: 68055
  • Gene Overview
    MyGene.info: DMAC2L
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:69724950-69744660 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 28.94 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915305
protein coding gene Chr12:69724927-69744665 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019800
protein coding gene Chr12:69432740-69455680 (+)
A/J MGP_AJ_G0019758
protein coding gene Chr12:66841293-66866402 (+)
AKR/J MGP_AKRJ_G0019734
protein coding gene Chr12:68841817-68869745 (+)
BALB/cJ MGP_BALBcJ_G0019738
protein coding gene Chr12:67296842-67328079 (+)
C3H/HeJ MGP_C3HHeJ_G0019544
protein coding gene Chr12:69307542-69338487 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020190
protein coding gene Chr12:71658874-71679758 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017810
protein coding gene Chr12:64376198-64404970 (+)
CAST/EiJ MGP_CASTEiJ_G0019095
protein coding gene Chr12:64060705-64088715 (+)
CBA/J MGP_CBAJ_G0019513
protein coding gene Chr12:74293087-74327218 (+)
DBA/2J MGP_DBA2J_G0019629
protein coding gene Chr12:66752783-66779475 (+)
FVB/NJ MGP_FVBNJ_G0019616
protein coding gene Chr12:65650909-65679089 (+)
LP/J MGP_LPJ_G0019701
protein coding gene Chr12:69374981-69410095 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019655
protein coding gene Chr12:77608553-77637862 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020225
protein coding gene Chr12:68322325-68349841 (+)
PWK/PhJ MGP_PWKPhJ_G0018860
protein coding gene Chr12:61024233-61048523 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018655
protein coding gene Chr12:62689483-62718355 (+)
WSB/EiJ MGP_WSBEiJ_G0019146
protein coding gene Chr12:68945070-68974595 (+)



Homology
more
  • Human Ortholog
    DMAC2L, distal membrane arm assembly complex 2 like
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DMAC2L, distal membrane arm assembly complex 2 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATP5S, ATPW, FB, HSU79253
  • Links
    NCBI Gene ID: 27109
    neXtProt AC: NX_Q99766
    UniProt: Q99766

  • Chr Location
    14q21.3; chr14:50311752-50326715 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054894 Ensembl Gene Model | MGI Sequence Detail 19711 C57BL/6J ±  kb
transcript ENSMUST00000220916 Ensembl | MGI Sequence Detail 1599 Not Applicable  
polypeptide ENSMUSP00000152430 Ensembl | MGI Sequence Detail 200 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:113816 Sanadi DR, et al., Evidence for the involvement of coupling factor B in the H+ channel of the mitochondrial H+-ATPase. Proc Natl Acad Sci U S A. 1984 Mar;81(5):1371-4
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory