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Mpnd Gene Detail
Summary
  • Symbol
    Mpnd
  • Name
    MPN domain containing
  • Synonyms
    E130307M08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915297
    NCBI Gene: 68047
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:56008880-56016790 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 29.11 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915297
protein coding gene Chr17:56005711-56016790 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023907
protein coding gene Chr17:57626781-57641849 (+)
A/J MGP_AJ_G0023867
protein coding gene Chr17:56076737-56088466 (+)
AKR/J MGP_AKRJ_G0023836
protein coding gene Chr17:56761701-56774250 (+)
BALB/cJ MGP_BALBcJ_G0023868
protein coding gene Chr17:55912082-55923578 (+)
C3H/HeJ MGP_C3HHeJ_G0023631
protein coding gene Chr17:57469565-57481821 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024312
protein coding gene Chr17:59910842-59925987 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021759
protein coding gene Chr17:52595037-52606339 (+)
CAST/EiJ MGP_CASTEiJ_G0023114
protein coding gene Chr17:57772297-57786186 (+)
CBA/J MGP_CBAJ_G0023608
protein coding gene Chr17:62213750-62231568 (+)
DBA/2J MGP_DBA2J_G0023736
protein coding gene Chr17:54811118-54823196 (+)
FVB/NJ MGP_FVBNJ_G0023702
protein coding gene Chr17:54326745-54340335 (+)
LP/J MGP_LPJ_G0023816
protein coding gene Chr17:58352521-58364590 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023729
protein coding gene Chr17:61778376-61791779 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024357
protein coding gene Chr17:57137695-57148555 (+)
PWK/PhJ MGP_PWKPhJ_G0022859
protein coding gene Chr17:54154618-54165440 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022671
protein coding gene Chr17:53900042-53914796 (+)
WSB/EiJ MGP_WSBEiJ_G0023178
protein coding gene Chr17:57749857-57762094 (+)



Homology
more
  • Human Ortholog
    MPND, MPN domain containing
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MPND, MPN domain containing
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 84954
    neXtProt AC: NX_Q8N594
    UniProt: Q8N594

  • Chr Location
    19p13.3; chr19:4343527-4360086 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68047 NCBI Gene Model | MGI Sequence Detail 7911 C57BL/6J ±  kb
transcript NM_026530 RefSeq | MGI Sequence Detail 1701 C57BL/6  
polypeptide Q3TV65 UniProt | EBI | MGI Sequence Detail 487 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory