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Rtraf Gene Detail
Summary
  • Symbol
    Rtraf
  • Name
    RNA transcription, translation and transport factor
  • Synonyms
    2700060E02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915295
    NCBI Gene: 68045
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:19861470-19873891 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 10.95 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    319 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915295
 protein coding gene Chr14:19861419-19873892 (-)
129S1/SvImJ ENSMUSG00200013389
 protein coding gene Chr14:11641135-11653607 (-)
A/J ENSMUSG00195020545
 protein coding gene Chr14:12733679-12746154 (-)
AKR/J ENSMUSG00220024899
 protein coding gene Chr14:11864177-11876651 (-)
BALB/cJ ENSMUSG00180033616
 protein coding gene Chr14:11828592-11841066 (-)
C3H/HeJ ENSMUSG00175020610
 protein coding gene Chr14:11889671-11902145 (-)
C57BL/6NJ ENSMUSG00215028296
 protein coding gene Chr14:12079211-12091686 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018978
 protein coding gene Chr14:12587770-12599992 (-)
CAST/EiJ ENSTCUG00005028493
 protein coding gene Chr14:12008527-12021016 (-)
CBA/J ENSMUSG00210025475
 protein coding gene Chr14:12114309-12126782 (-)
DBA/2J ENSMUSG00185036253
 protein coding gene Chr14:16399326-16411798 (-)
FVB/NJ ENSMUSG00205032301
 protein coding gene Chr14:11954837-11967309 (-)
JF1/MsJ ENSUMUG00000037165
 protein coding gene Chr14:23612162-23624682 (-)
LP/J ENSMUSG00230034302
 protein coding gene Chr14:23681178-23693650 (-)
NOD/ShiLtJ ENSMUSG00190023843
 protein coding gene Chr14:12113183-12125655 (-)
NZO/HlLtJ ENSMUSG00225036277
 protein coding gene Chr14:17922755-17935227 (-)
PWK/PhJ ENSLUMG00010019309
 protein coding gene Chr14:188249-200710 (-)
SPRET/EiJ ENSMSPG00010026815
 protein coding gene Chr14:13743901-13756511 (-)
WSB/EiJ ENSIUOG00005032311
 protein coding gene Chr14:11944890-11957361 (-)



Homology
more
  • Human Ortholog
    RTRAF, RNA transcription, translation and transport factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RTRAF, RNA transcription, translation and transport factor
  • Synonyms
    C14orf166, CGI-99, CGI99, CLE, CLE7, hCLE, hCLE1, LCRP369, RLLM1, TSLIG4
  • Links
    NCBI Gene ID: 51637
    UniProt: Q9Y224

  • Chr Location
    14q22.1; chr14:51989441-52010694 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    654
  • Tissues
    40
  • cDNA Data
    108
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68045 NCBI Gene Model | MGI Sequence Detail 12422 C57BL/6J ±  kb
transcript NM_026528 RefSeq | MGI Sequence Detail 1510 C57BL/6  
polypeptide Q9CQE8 UniProt | EBI | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000036367 protein C14orf166
    (term hierarchy)
  • InterPro Domains
    IPR019265 RNA transcription, translation and transport factor protein
  • GlyGen
    Q9CQE8 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 108
    cDNA 108

    Microarray probesets 6
Other
Accession IDs
less
MGI:5908142
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory