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Chac2 Gene Detail
Summary
  • Symbol
    Chac2
  • Name
    ChaC, cation transport regulator 2
  • Synonyms
    2510006C20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915294
    NCBI Gene: 68044
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:30976707-30986350 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 18.20 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915294
protein coding gene Chr11:30976707-30986365 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018120
protein coding gene Chr11:29095550-29108715 (-)
A/J MGP_AJ_G0018093
protein coding gene Chr11:28011942-28021467 (-)
AKR/J MGP_AKRJ_G0018057
protein coding gene Chr11:28897848-28907149 (-)
BALB/cJ MGP_BALBcJ_G0018062
protein coding gene Chr11:28216006-28225285 (-)
C3H/HeJ MGP_C3HHeJ_G0017875
protein coding gene Chr11:28849383-28859585 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018513
protein coding gene Chr11:30057519-30067861 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016169
protein coding gene Chr11:26529624-26539081 (-)
CAST/EiJ MGP_CASTEiJ_G0017437
protein coding gene Chr11:28923458-28935113 (-)
CBA/J MGP_CBAJ_G0017848
protein coding gene Chr11:31501676-31512945 (-)
DBA/2J MGP_DBA2J_G0017958
protein coding gene Chr11:27834020-27843161 (-)
FVB/NJ MGP_FVBNJ_G0017952
protein coding gene Chr11:27624777-27634042 (-)
LP/J MGP_LPJ_G0018030
protein coding gene Chr11:29336849-29346384 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017976
protein coding gene Chr11:32561193-32576305 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018554
protein coding gene Chr11:29001504-29013605 (-)
PWK/PhJ MGP_PWKPhJ_G0017219
protein coding gene Chr11:27933253-27943007 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017013
protein coding gene Chr11:28726783-28736369 (-)
WSB/EiJ MGP_WSBEiJ_G0017489
protein coding gene Chr11:28687409-28702296 (-)



Homology
more
  • Human Ortholog
    CHAC2, ChaC cation transport regulator homolog 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHAC2, ChaC cation transport regulator homolog 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GCG1
  • Links
    NCBI Gene ID: 494143
    neXtProt AC: NX_Q8WUX2
    UniProt: Q8WUX2

  • Chr Location
    2p16.2; chr2:53767792-53775150 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 48696
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CHAC2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Chac2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020309 Ensembl Gene Model | MGI Sequence Detail 9644 C57BL/6J ±  kb
transcript ENSMUST00000101394 Ensembl | MGI Sequence Detail 1315 Not Applicable  
polypeptide ENSMUSP00000098942 Ensembl | MGI Sequence Detail 178 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005399 glutathione-specific gamma-glutamylcyclotransferase 2
  • EC
  • InterPro Domains
    IPR013024 Gamma-glutamyl cyclotransferase-like
    IPR036568 Gamma-glutamyl cyclotransferase-like superfamily
    IPR006840 Glutathione-specific gamma-glutamylcyclotransferase
Molecular
Reagents
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  • All nucleic 26
    cDNA 26

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:238477 Kaur A, et al., ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione. J Biol Chem. 2017 Jan 13;292(2):638-651

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory