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Rpl22l1 Gene Detail
Summary
  • Symbol
    Rpl22l1
  • Name
    ribosomal protein L22 like 1
  • Synonyms
    3110001N18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915278
    NCBI Gene: 68028
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:28805444-28807424 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 12.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915278
protein coding gene Chr3:28805436-28807424 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027118
protein coding gene Chr3:26200233-26205321 (+)
A/J MGP_AJ_G0027078
protein coding gene Chr3:25927505-25929493 (+)
AKR/J MGP_AKRJ_G0027047
protein coding gene Chr3:26311615-26313603 (+)
BALB/cJ MGP_BALBcJ_G0027090
protein coding gene Chr3:25629720-25633458 (+)
C3H/HeJ MGP_C3HHeJ_G0026832
protein coding gene Chr3:26348204-26350192 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027535
protein coding gene Chr3:27593791-27595779 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024897
protein coding gene Chr3:23944885-23946878 (+)
CAST/EiJ MGP_CASTEiJ_G0026286
protein coding gene Chr3:26202832-26204820 (+)
CBA/J MGP_CBAJ_G0026810
protein coding gene Chr3:28352557-28354545 (+)
DBA/2J MGP_DBA2J_G0026944
protein coding gene Chr3:25510143-25512362 (+)
FVB/NJ MGP_FVBNJ_G0026911
protein coding gene Chr3:24965750-24968182 (+)
LP/J MGP_LPJ_G0027055
protein coding gene Chr3:26893805-26896894 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026932
protein coding gene Chr3:30889396-30906158 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027595
protein coding gene Chr3:26052157-26054624 (+)
PWK/PhJ MGP_PWKPhJ_G0026019
protein coding gene Chr3:24991263-24993367 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025831
protein coding gene Chr3:25589343-25591390 (+)
WSB/EiJ MGP_WSBEiJ_G0026360
protein coding gene Chr3:26100253-26102566 (+)



Homology
more
  • Human Ortholog
    RPL22L1, ribosomal protein L22 like 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    RPL22L1, ribosomal protein L22 like 1
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 200916
    neXtProt AC: NX_Q6P5R6
    UniProt: Q6P5R6

  • Chr Location
    3q26.2; chr3:170864875-170870256 (-)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal development at E9.5 and die by E12.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68028 NCBI Gene Model | MGI Sequence Detail 1981 C57BL/6J ±  kb
transcript NR_154888 RefSeq | MGI Sequence Detail 556 C57BL/6  
polypeptide Q9D7S7 UniProt | EBI | MGI Sequence Detail 122 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139906
References
more
  • Summaries
    All 26
    Diseases 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:251438 Zhang Y, et al., Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep. 2017 Jan 10;18(2):545-556

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory