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Hist1h2bc Gene Detail
Summary
  • Symbol
    Hist1h2bc
  • Name
    histone cluster 1, H2bc
  • Synonyms
    2610022J01Rik, H2bfs
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915274
    NCBI Gene: 68024
  • Member of
    Hist1 cluster
  • Gene Overview
    MyGene.info: HIST1H2BI
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23684199-23692480 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.87 cM, cytoband A2-A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915274
protein coding gene Chr13:23684199-23692908 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020355
protein coding gene Chr13:21117647-21126410 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0020287
protein coding gene Chr13:20984691-20993394 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0020108
protein coding gene Chr13:21052554-21061870 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018327
protein coding gene Chr13:19517517-19525629 (+)
CAST/EiJ MGP_CASTEiJ_G0019625
protein coding gene Chr13:20735912-20744338 (+)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0020187
protein coding gene Chr13:20263033-20271536 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0020259
protein coding gene Chr13:21428779-21438430 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020199
protein coding gene Chr13:23043964-23054716 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020781
protein coding gene Chr13:20833742-20842809 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    HIST1H2BI, histone cluster 1 H2B family member i
  • Vertebrate Orthologs
    6
  • Human Ortholog
    HIST1H2BI, histone cluster 1 H2B family member i
    Orthology source: HomoloGene
  • Synonyms
    H2BFK, H2B/k
  • Links
    NCBI Gene ID: 8346
    neXtProt AC: NX_P62807
    UniProt: P62807

  • Chr Location
    6p22.2; chr6:26272976-26273412 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    39
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    36
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Hist1h2bc
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68024 NCBI Gene Model | MGI Sequence Detail 8282 C57BL/6J ±  kb
transcript NM_023422 RefSeq | MGI Sequence Detail 728 C57BL/6  
polypeptide NP_001277309 RefSeq | MGI Sequence Detail 126 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 138
    Genomic 1
    cDNA 134
    Primer pair 2
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145542
References
more
  • Summaries
    All 44
    Developmental Gene Expression 7
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:233532 Scekic-Zahirovic J, et al., Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 May 17;35(10):1077-97

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory