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Mrm2 Gene Detail
Summary
  • Symbol
    Mrm2
  • Name
    mitochondrial rRNA methyltransferase 2
  • Synonyms
    2310037B18Rik, Ftsj2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915267
    NCBI Gene: 68017
Location & Maps
more
  • Sequence Map
    Chr5:140327674-140331898 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4225 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 78.94 cM, cytoband G1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MRM2, mitochondrial rRNA methyltransferase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MRM2, mitochondrial rRNA methyltransferase 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FJH1, FTSJ2, HEL97, RRMJ2
  • Links
    NCBI Gene ID: 29960
    neXtProt AC: NX_Q9UI43

  • Chr Location
    7p22; chr7:2234291-2242198 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    3
  • Targeted
    3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025889 VEGA Gene Model | MGI Sequence Detail 4225 C57BL/6J ±  kb
transcript OTTMUST00000063800 VEGA | MGI Sequence Detail 1443 Not Applicable  
polypeptide OTTMUSP00000031606 VEGA | MGI Sequence Detail 246 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    13 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031650 ribosomal RNA methyltransferase 2
  • EC
  • InterPro Domains
    IPR015507 Ribosomal RNA large subunit methyltransferase E
    IPR002877 Ribosomal RNA methyltransferase FtsJ domain
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:172928 Segal DM, et al., A nucleolar 2'-O-methyltransferase. Specificity and evidence for its role in the methylation of mouse 28 S precursor ribosomal RNA. J Biol Chem. 1991 Dec 25;266(36):24385-9
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory